Progress in the Development of Biosensors Based on Peptide–Copper Coordination Interaction
Copper ions, as the active centers of natural enzymes, play an important role in many physiological processes. Copper ion-based catalysts which mimic the activity of enzymes have been widely used in the field of industrial catalysis and sensing devices. As an important class of small biological mole...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/12/10/809 |
| _version_ | 1797474823247495168 |
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| author | Gang Liu Ning Xia Linxu Tian Zhifang Sun Lin Liu |
| author_facet | Gang Liu Ning Xia Linxu Tian Zhifang Sun Lin Liu |
| author_sort | Gang Liu |
| collection | DOAJ |
| description | Copper ions, as the active centers of natural enzymes, play an important role in many physiological processes. Copper ion-based catalysts which mimic the activity of enzymes have been widely used in the field of industrial catalysis and sensing devices. As an important class of small biological molecules, peptides have the advantages of easy synthesis, excellent biocompatibility, low toxicity, and good water solubility. The peptide–copper complexes exhibit the characteristics of low molecular weight, high tenability, and unique catalytic and photophysical properties. Biosensors with peptide–copper complexes as the signal probes have promising application prospects in environmental monitoring and biomedical analysis and diagnosis. In this review, we discussed the design and application of fluorescent, colorimetric and electrochemical biosensors based on the peptide–copper coordination interaction. |
| first_indexed | 2024-03-09T20:35:36Z |
| format | Article |
| id | doaj.art-0ac06dfd7bad4f0d8a13f29bdd54c899 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-09T20:35:36Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-0ac06dfd7bad4f0d8a13f29bdd54c8992023-11-23T23:11:00ZengMDPI AGBiosensors2079-63742022-09-01121080910.3390/bios12100809Progress in the Development of Biosensors Based on Peptide–Copper Coordination InteractionGang Liu0Ning Xia1Linxu Tian2Zhifang Sun3Lin Liu4College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, ChinaCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, ChinaCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, ChinaCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, ChinaCollege of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, ChinaCopper ions, as the active centers of natural enzymes, play an important role in many physiological processes. Copper ion-based catalysts which mimic the activity of enzymes have been widely used in the field of industrial catalysis and sensing devices. As an important class of small biological molecules, peptides have the advantages of easy synthesis, excellent biocompatibility, low toxicity, and good water solubility. The peptide–copper complexes exhibit the characteristics of low molecular weight, high tenability, and unique catalytic and photophysical properties. Biosensors with peptide–copper complexes as the signal probes have promising application prospects in environmental monitoring and biomedical analysis and diagnosis. In this review, we discussed the design and application of fluorescent, colorimetric and electrochemical biosensors based on the peptide–copper coordination interaction.https://www.mdpi.com/2079-6374/12/10/809peptidecopper ionfluorescent assaycolorimetryelectrochemical biosensor |
| spellingShingle | Gang Liu Ning Xia Linxu Tian Zhifang Sun Lin Liu Progress in the Development of Biosensors Based on Peptide–Copper Coordination Interaction Biosensors peptide copper ion fluorescent assay colorimetry electrochemical biosensor |
| title | Progress in the Development of Biosensors Based on Peptide–Copper Coordination Interaction |
| title_full | Progress in the Development of Biosensors Based on Peptide–Copper Coordination Interaction |
| title_fullStr | Progress in the Development of Biosensors Based on Peptide–Copper Coordination Interaction |
| title_full_unstemmed | Progress in the Development of Biosensors Based on Peptide–Copper Coordination Interaction |
| title_short | Progress in the Development of Biosensors Based on Peptide–Copper Coordination Interaction |
| title_sort | progress in the development of biosensors based on peptide copper coordination interaction |
| topic | peptide copper ion fluorescent assay colorimetry electrochemical biosensor |
| url | https://www.mdpi.com/2079-6374/12/10/809 |
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