Effect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia)
Puerarin is an isoflavone extracted from Gegen (Pueraria lobata) and has been widely utilized to treat various human diseases; however, information regarding its benefits in animal production is limited. In this study, we aimed to investigate the influence of dietary puerarin supplementation on grow...
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2024-01-01
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| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/61/0/61_2024003/_html/-char/en |
| _version_ | 1797335361780711424 |
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| author | Runzhi Wang Tingting Li Zaixu Pan Hui Chen Shanjin Xu Xixue Lu Kai Shi Bang Bian Guansuo Wu |
| author_facet | Runzhi Wang Tingting Li Zaixu Pan Hui Chen Shanjin Xu Xixue Lu Kai Shi Bang Bian Guansuo Wu |
| author_sort | Runzhi Wang |
| collection | DOAJ |
| description | Puerarin is an isoflavone extracted from Gegen (Pueraria lobata) and has been widely utilized to treat various human diseases; however, information regarding its benefits in animal production is limited. In this study, we aimed to investigate the influence of dietary puerarin supplementation on growth performance, immune organ index, immunoglobulin profile, antioxidant capacity, and intestinal morphology in pigeons. In total, 375 healthy 28-day-old White King pigeons were randomly divided into five groups, each consisting of five replicates and 15 pigeons per replicate. Each group was administered one of five dietary treatments: the basal diet, or the basal diet supplemented with 40, 80, 120, or 160 mg/kg puerarin. Treatment duration was 30 days following a 7-day acclimation period. Puerarin treatment did not significantly alter the growth performance of pigeons but afforded a significant linear enhancement in the thymus index (P < 0.05). Additionally, puerarin supplementation significantly increased serum immunoglobulin A and immunoglobulin M levels in pigeons in a linear manner (P < 0.05). Similarly, puerarin significantly and linearly increased the activities of total antioxidant capacity, superoxide dismutase, glutathione, and catalase in the serum and liver, and decreased the malondialdehyde content (P < 0.05). Moreover, the villus height (VH), crypt depth (CD), and VH/CD ratio of the small intestine (including the duodenum, jejunum, and ileum) increased linearly upon puerarin supplementation (P < 0.05). Collectively, these results indicate that puerarin supplementation could improve the immune response, antioxidant capacity, and intestinal morphology of pigeons. |
| first_indexed | 2024-03-08T08:35:55Z |
| format | Article |
| id | doaj.art-0ac24bea92294dba8eb6679656ed1ade |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-08T08:35:55Z |
| publishDate | 2024-01-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-0ac24bea92294dba8eb6679656ed1ade2024-02-02T00:57:39ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862024-01-0161010.2141/jpsa.2024003jpsaEffect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia)Runzhi Wang0Tingting Li1Zaixu Pan2Hui Chen3Shanjin Xu4Xixue Lu5Kai Shi6Bang Bian7Guansuo Wu8Nanjing Institute of Animal Husbandry and Poultry Science, Nanjing 210036, ChinaWenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325011, ChinaNanjing Dongchen Pigeon Industry Co., Ltd., Nanjing 210000, ChinaNanjing Dongchen Pigeon Industry Co., Ltd., Nanjing 210000, ChinaNanjing Dongchen Pigeon Industry Co., Ltd., Nanjing 210000, ChinaCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaNanjing Institute of Animal Husbandry and Poultry Science, Nanjing 210036, ChinaNanjing Institute of Animal Husbandry and Poultry Science, Nanjing 210036, ChinaPuerarin is an isoflavone extracted from Gegen (Pueraria lobata) and has been widely utilized to treat various human diseases; however, information regarding its benefits in animal production is limited. In this study, we aimed to investigate the influence of dietary puerarin supplementation on growth performance, immune organ index, immunoglobulin profile, antioxidant capacity, and intestinal morphology in pigeons. In total, 375 healthy 28-day-old White King pigeons were randomly divided into five groups, each consisting of five replicates and 15 pigeons per replicate. Each group was administered one of five dietary treatments: the basal diet, or the basal diet supplemented with 40, 80, 120, or 160 mg/kg puerarin. Treatment duration was 30 days following a 7-day acclimation period. Puerarin treatment did not significantly alter the growth performance of pigeons but afforded a significant linear enhancement in the thymus index (P < 0.05). Additionally, puerarin supplementation significantly increased serum immunoglobulin A and immunoglobulin M levels in pigeons in a linear manner (P < 0.05). Similarly, puerarin significantly and linearly increased the activities of total antioxidant capacity, superoxide dismutase, glutathione, and catalase in the serum and liver, and decreased the malondialdehyde content (P < 0.05). Moreover, the villus height (VH), crypt depth (CD), and VH/CD ratio of the small intestine (including the duodenum, jejunum, and ileum) increased linearly upon puerarin supplementation (P < 0.05). Collectively, these results indicate that puerarin supplementation could improve the immune response, antioxidant capacity, and intestinal morphology of pigeons.https://www.jstage.jst.go.jp/article/jpsa/61/0/61_2024003/_html/-char/enantioxidant capacityimmune responseintestinal morphologypigeonpuerarin |
| spellingShingle | Runzhi Wang Tingting Li Zaixu Pan Hui Chen Shanjin Xu Xixue Lu Kai Shi Bang Bian Guansuo Wu Effect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia) The Journal of Poultry Science antioxidant capacity immune response intestinal morphology pigeon puerarin |
| title | Effect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia) |
| title_full | Effect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia) |
| title_fullStr | Effect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia) |
| title_full_unstemmed | Effect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia) |
| title_short | Effect of Dietary Puerarin Supplementation on Growth Performance, Immune Response, Antioxidant Capacity, and Intestinal Morphology in Domestic Pigeons (Columba livia) |
| title_sort | effect of dietary puerarin supplementation on growth performance immune response antioxidant capacity and intestinal morphology in domestic pigeons columba livia |
| topic | antioxidant capacity immune response intestinal morphology pigeon puerarin |
| url | https://www.jstage.jst.go.jp/article/jpsa/61/0/61_2024003/_html/-char/en |
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