A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature
Abstract Background Aerococcus urinae is a gram-positive, alpha-hemolytic coccus bacterium primarily implicated in less than 1 % of all symptomatic urinary tract infections. Risk factors for disease include male gender, advanced age, and comorbid genitourinary tract pathology. Infections beyond the...
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12879-018-3414-0 |
| _version_ | 1819006920734801920 |
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| author | Joseph M. Yabes Serafim Perdikis David B. Graham Ana Markelz |
| author_facet | Joseph M. Yabes Serafim Perdikis David B. Graham Ana Markelz |
| author_sort | Joseph M. Yabes |
| collection | DOAJ |
| description | Abstract Background Aerococcus urinae is a gram-positive, alpha-hemolytic coccus bacterium primarily implicated in less than 1 % of all symptomatic urinary tract infections. Risk factors for disease include male gender, advanced age, and comorbid genitourinary tract pathology. Infections beyond the genitourinary tract are rare, though spondylodiscitis, perineal abscesses, lymphadenitis, bacteremia, meningitis, and endocarditis have been reported. Less than fifty cases of A. urinae infective endocarditis (IE) have been described in the literature. The rare occurrence of A. urinae in human infections and resultant lack of randomized controlled trials have resulted in a significant degree of clinical uncertainty in the management of A. urinae IE. Case presentation We present an unusual case of a forty-three year-old male with A. urinae infective endocarditis (IE) who was successfully treated with mitral valve replacement and six weeks of penicillin/gentamicin therapy. In addition, we include a comprehensive review of all reported cases of IE due to A. urinae with specific attention to therapeutic regimens and treatment durations. Conclusion Recent advances in diagnostic technology have led to an increase in the frequency A. urinae is diagnosed. Reviewing cases of Aerococcus urinae infections, their clinical courses and subsequent management can assist future healthcare providers and their patients. |
| first_indexed | 2024-12-21T00:16:21Z |
| format | Article |
| id | doaj.art-0ac4322c62b44d58b980272b72d03cbc |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-21T00:16:21Z |
| publishDate | 2018-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-0ac4322c62b44d58b980272b72d03cbc2022-12-21T19:22:12ZengBMCBMC Infectious Diseases1471-23342018-10-011811710.1186/s12879-018-3414-0A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literatureJoseph M. Yabes0Serafim Perdikis1David B. Graham2Ana Markelz3Brooke Army Medical Center, Department of Infectious DiseaseBrooke Army Medical Center, Department of Internal MedicineBrooke Army Medical Center, Department of Cardiothoracic SurgeryBrooke Army Medical Center, Department of Infectious DiseaseAbstract Background Aerococcus urinae is a gram-positive, alpha-hemolytic coccus bacterium primarily implicated in less than 1 % of all symptomatic urinary tract infections. Risk factors for disease include male gender, advanced age, and comorbid genitourinary tract pathology. Infections beyond the genitourinary tract are rare, though spondylodiscitis, perineal abscesses, lymphadenitis, bacteremia, meningitis, and endocarditis have been reported. Less than fifty cases of A. urinae infective endocarditis (IE) have been described in the literature. The rare occurrence of A. urinae in human infections and resultant lack of randomized controlled trials have resulted in a significant degree of clinical uncertainty in the management of A. urinae IE. Case presentation We present an unusual case of a forty-three year-old male with A. urinae infective endocarditis (IE) who was successfully treated with mitral valve replacement and six weeks of penicillin/gentamicin therapy. In addition, we include a comprehensive review of all reported cases of IE due to A. urinae with specific attention to therapeutic regimens and treatment durations. Conclusion Recent advances in diagnostic technology have led to an increase in the frequency A. urinae is diagnosed. Reviewing cases of Aerococcus urinae infections, their clinical courses and subsequent management can assist future healthcare providers and their patients.http://link.springer.com/article/10.1186/s12879-018-3414-0Aerococcus urinaeInfective endocarditisAerococci |
| spellingShingle | Joseph M. Yabes Serafim Perdikis David B. Graham Ana Markelz A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature BMC Infectious Diseases Aerococcus urinae Infective endocarditis Aerococci |
| title | A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature |
| title_full | A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature |
| title_fullStr | A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature |
| title_full_unstemmed | A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature |
| title_short | A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature |
| title_sort | rare case of aerococcus urinae infective endocarditis in an atypically young male case report and review of the literature |
| topic | Aerococcus urinae Infective endocarditis Aerococci |
| url | http://link.springer.com/article/10.1186/s12879-018-3414-0 |
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