Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review
Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, incl...
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| Format: | Article |
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Frontiers Media S.A.
2021-02-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2021.591796/full |
| _version_ | 1818342740517191680 |
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| author | Cheng Zhang Tianjia Zhang Tengyu Geng Xudong Wang Kaili Lin Penglai Wang Penglai Wang |
| author_facet | Cheng Zhang Tianjia Zhang Tengyu Geng Xudong Wang Kaili Lin Penglai Wang Penglai Wang |
| author_sort | Cheng Zhang |
| collection | DOAJ |
| description | Implant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, including osteoporosis, because of a non-ideal local microenvironment. Clinically common physical and chemical modifications are used to change the roughness of the implant surface to promote osseointegration, but they have limitations in promoting osteoinduction and inhibiting bone resorption. Recently, many researchers have focused on the study of bioactive modification of implants and have achieved promising results. Herein we have summarized the progress in bioactive modification strategy to promote osseointegration by regulating the local osteoporotic microenvironment. |
| first_indexed | 2024-12-13T16:19:30Z |
| format | Article |
| id | doaj.art-0ac4aacbd6b74ef5b304ae0661c4d377 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-13T16:19:30Z |
| publishDate | 2021-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-0ac4aacbd6b74ef5b304ae0661c4d3772022-12-21T23:38:45ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852021-02-01910.3389/fbioe.2021.591796591796Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A ReviewCheng Zhang0Tianjia Zhang1Tengyu Geng2Xudong Wang3Kaili Lin4Penglai Wang5Penglai Wang6School of Stomatology, Xuzhou Medical University, Xuzhou, ChinaDepartment of Oral & Cranio-Maxillofacial Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, ChinaAffiliated Stomatological Hospital of Xuzhou Medical University, Xuzhou, ChinaDepartment of Oral & Cranio-Maxillofacial Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, ChinaDepartment of Oral & Cranio-Maxillofacial Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, ChinaSchool of Stomatology, Xuzhou Medical University, Xuzhou, ChinaAffiliated Stomatological Hospital of Xuzhou Medical University, Xuzhou, ChinaImplant-supported dentures are widely used in patients with defect or loss of dentition because these have higher chewing efficiency and do not damage the adjacent teeth compared with fixed or removable denture. An implant-supported denture carries the risk of failure in some systemic diseases, including osteoporosis, because of a non-ideal local microenvironment. Clinically common physical and chemical modifications are used to change the roughness of the implant surface to promote osseointegration, but they have limitations in promoting osteoinduction and inhibiting bone resorption. Recently, many researchers have focused on the study of bioactive modification of implants and have achieved promising results. Herein we have summarized the progress in bioactive modification strategy to promote osseointegration by regulating the local osteoporotic microenvironment.https://www.frontiersin.org/articles/10.3389/fbioe.2021.591796/fulldental implantsbioactive agentsosseointegrationosteoporosiscontrolled release |
| spellingShingle | Cheng Zhang Tianjia Zhang Tengyu Geng Xudong Wang Kaili Lin Penglai Wang Penglai Wang Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review Frontiers in Bioengineering and Biotechnology dental implants bioactive agents osseointegration osteoporosis controlled release |
| title | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
| title_full | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
| title_fullStr | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
| title_full_unstemmed | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
| title_short | Dental Implants Loaded With Bioactive Agents Promote Osseointegration in Osteoporosis: A Review |
| title_sort | dental implants loaded with bioactive agents promote osseointegration in osteoporosis a review |
| topic | dental implants bioactive agents osseointegration osteoporosis controlled release |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2021.591796/full |
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