Implementation of an evidence-based management algorithm for patients with chronic pancreatitis (COMBO trial): study protocol for a stepped-wedge cluster-randomized controlled trial

Implementation of an evidence-based management algorithm for patients with chronic pancreatitis (COMBO trial): study protocol for a stepped-wedge cluster-randomized controlled trial

Abstract Background Chronic pancreatitis (CP) is an inflammatory disease that may be complicated by abdominal pain, pancreatic dysfunction, nutritional deficiencies, and diminished bone density. Importantly, it is also associated with a substantially impaired quality of life and reduced life expecta...

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Bibliographic Details
Main Authors: Florence E. M. de Rijk, Charlotte L. van Veldhuisen, Marc G. Besselink, Jeanin E. van Hooft, Hjalmar C. van Santvoort, Erwin J. M. van Geenen, Cornelis H. van Werkhoven, Pieter Jan F. de Jonge, Marco J. Bruno, Robert C. Verdonk, for the Dutch Pancreatitis Study Group
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Trials
Subjects:
Chronic pancreatitis
Management algorithm
Integrated care
Evidence-based
Quality of life
Pain severity
Online Access:https://doi.org/10.1186/s13063-022-07044-8

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