Next Generation Influenza Vaccines: Looking into the Crystal Ball
Influenza infections are responsible for significant number of deaths and overwhelming costs worldwide every year. Vaccination represents the only cost-efficient alternative to address this major problem in human health. However, current vaccines are fraught by many limitations, being far from optim...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Vaccines |
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| Online Access: | https://www.mdpi.com/2076-393X/8/3/464 |
| _version_ | 1827708355860234240 |
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| author | Carlos Alberto Guzmán |
| author_facet | Carlos Alberto Guzmán |
| author_sort | Carlos Alberto Guzmán |
| collection | DOAJ |
| description | Influenza infections are responsible for significant number of deaths and overwhelming costs worldwide every year. Vaccination represents the only cost-efficient alternative to address this major problem in human health. However, current vaccines are fraught by many limitations, being far from optimal. Among them, the need to upgrade vaccines every year through a time-consuming process open to different caveats, and the critical fact that they exhibit poorer efficacy in individuals who are at high risk for severe infections. Where are we? How can knowledge and technologies contribute towards removing current roadblocks? What does the future offer in terms of next generation vaccines? |
| first_indexed | 2024-03-10T17:02:30Z |
| format | Article |
| id | doaj.art-0acb2efa98c74cbdbee16273f22c2a7e |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-03-10T17:02:30Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-0acb2efa98c74cbdbee16273f22c2a7e2023-11-20T10:54:02ZengMDPI AGVaccines2076-393X2020-08-018346410.3390/vaccines8030464Next Generation Influenza Vaccines: Looking into the Crystal BallCarlos Alberto Guzmán0Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, GermanyInfluenza infections are responsible for significant number of deaths and overwhelming costs worldwide every year. Vaccination represents the only cost-efficient alternative to address this major problem in human health. However, current vaccines are fraught by many limitations, being far from optimal. Among them, the need to upgrade vaccines every year through a time-consuming process open to different caveats, and the critical fact that they exhibit poorer efficacy in individuals who are at high risk for severe infections. Where are we? How can knowledge and technologies contribute towards removing current roadblocks? What does the future offer in terms of next generation vaccines?https://www.mdpi.com/2076-393X/8/3/464influenzainfluenza vaccineuniversal influenza vaccinenext generation influenza vaccineegg-adaptationT cell influenza vaccine |
| spellingShingle | Carlos Alberto Guzmán Next Generation Influenza Vaccines: Looking into the Crystal Ball Vaccines influenza influenza vaccine universal influenza vaccine next generation influenza vaccine egg-adaptation T cell influenza vaccine |
| title | Next Generation Influenza Vaccines: Looking into the Crystal Ball |
| title_full | Next Generation Influenza Vaccines: Looking into the Crystal Ball |
| title_fullStr | Next Generation Influenza Vaccines: Looking into the Crystal Ball |
| title_full_unstemmed | Next Generation Influenza Vaccines: Looking into the Crystal Ball |
| title_short | Next Generation Influenza Vaccines: Looking into the Crystal Ball |
| title_sort | next generation influenza vaccines looking into the crystal ball |
| topic | influenza influenza vaccine universal influenza vaccine next generation influenza vaccine egg-adaptation T cell influenza vaccine |
| url | https://www.mdpi.com/2076-393X/8/3/464 |
| work_keys_str_mv | AT carlosalbertoguzman nextgenerationinfluenzavaccineslookingintothecrystalball |