The Application of Porphyrins and Their Analogues for Inactivation of Viruses

The problem of treating viral infections is extremely relevant due to both the emergence of new viral diseases and to the low effectiveness of existing approaches to the treatment of known viral infections. This review focuses on the application of porphyrin, chlorin, and phthalocyanine series for c...

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Main Authors: Natalya Sh. Lebedeva, Yury A. Gubarev, Mikhail O. Koifman, Oskar I. Koifman
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/19/4368
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author Natalya Sh. Lebedeva
Yury A. Gubarev
Mikhail O. Koifman
Oskar I. Koifman
author_facet Natalya Sh. Lebedeva
Yury A. Gubarev
Mikhail O. Koifman
Oskar I. Koifman
author_sort Natalya Sh. Lebedeva
collection DOAJ
description The problem of treating viral infections is extremely relevant due to both the emergence of new viral diseases and to the low effectiveness of existing approaches to the treatment of known viral infections. This review focuses on the application of porphyrin, chlorin, and phthalocyanine series for combating viral infections by chemical and photochemical inactivation methods. The purpose of this review paper is to summarize the main approaches developed to date in the chemical and photodynamic inactivation of human and animal viruses using porphyrins and their analogues and to analyze and discuss the information on viral targets and antiviral activity of porphyrins, chlorins, of their conjugates with organic/inorganic compounds obtained in the last 10–15 years in order to identify the most promising areas.
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spelling doaj.art-0acc382f094949ad84dbaed31e7ba1b22023-11-20T14:47:25ZengMDPI AGMolecules1420-30492020-09-012519436810.3390/molecules25194368The Application of Porphyrins and Their Analogues for Inactivation of VirusesNatalya Sh. Lebedeva0Yury A. Gubarev1Mikhail O. Koifman2Oskar I. Koifman3Laboratory 1-7. Physical Chemistry of Solutions of Macrocyclic Compounds, G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, 153045 Ivanovo, RussiaLaboratory 1-7. Physical Chemistry of Solutions of Macrocyclic Compounds, G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, 153045 Ivanovo, RussiaDepartment of Chemistry and Technology of Macromolecular Compounds, Ivanovo State University of Chemistry and Technology, 153000 Ivanovo, RussiaDepartment of Chemistry and Technology of Macromolecular Compounds, Ivanovo State University of Chemistry and Technology, 153000 Ivanovo, RussiaThe problem of treating viral infections is extremely relevant due to both the emergence of new viral diseases and to the low effectiveness of existing approaches to the treatment of known viral infections. This review focuses on the application of porphyrin, chlorin, and phthalocyanine series for combating viral infections by chemical and photochemical inactivation methods. The purpose of this review paper is to summarize the main approaches developed to date in the chemical and photodynamic inactivation of human and animal viruses using porphyrins and their analogues and to analyze and discuss the information on viral targets and antiviral activity of porphyrins, chlorins, of their conjugates with organic/inorganic compounds obtained in the last 10–15 years in order to identify the most promising areas.https://www.mdpi.com/1420-3049/25/19/4368virusesSARS-CoVchlorinDNAporphyrinsphthalocyanines
spellingShingle Natalya Sh. Lebedeva
Yury A. Gubarev
Mikhail O. Koifman
Oskar I. Koifman
The Application of Porphyrins and Their Analogues for Inactivation of Viruses
Molecules
viruses
SARS-CoV
chlorin
DNA
porphyrins
phthalocyanines
title The Application of Porphyrins and Their Analogues for Inactivation of Viruses
title_full The Application of Porphyrins and Their Analogues for Inactivation of Viruses
title_fullStr The Application of Porphyrins and Their Analogues for Inactivation of Viruses
title_full_unstemmed The Application of Porphyrins and Their Analogues for Inactivation of Viruses
title_short The Application of Porphyrins and Their Analogues for Inactivation of Viruses
title_sort application of porphyrins and their analogues for inactivation of viruses
topic viruses
SARS-CoV
chlorin
DNA
porphyrins
phthalocyanines
url https://www.mdpi.com/1420-3049/25/19/4368
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