Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation

Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is an important regulator of cell death pathways during embryogenesis and in infection/inflammation. Here authors show that tyrosine phosphorylation of RIPK1 by upstream kinases limits systemic inflammation and regulates haematopoietic h...

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Bibliographic Details
Main Authors: Hailin Tu, Weihang Xiong, Jie Zhang, Xueqiang Zhao, Xin Lin
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34080-4

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