Low levels of CIITA and high levels of SOCS1 predict COVID-19 disease severity in children and adults

Summary: It is unclear why COVID-19 ranges from asymptomatic to severe. When SARS-CoV-2 is detected, interferon (IFN) response is activated. When it is insufficient or delayed, it might lead to overproduction of cytokines and severe COVID-19. The aim was to compare cytokine and IFN patterns in child...

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Bibliographic Details
Main Authors: Mònica Girona-Alarcon, Guillermo Argüello, Ana Esteve-Sole, Sara Bobillo-Perez, Xavier Paolo Burgos-Artizzu, Elisenda Bonet-Carne, Anna Mensa-Vilaró, Anna Codina, María Hernández-Garcia, Cristina Jou, Laia Alsina, Iolanda Jordan
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015650