Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit Experience
Objective: This study was conducted to assess the frequency of different microbial isolates and their antibiotic resistance pattern in patients admitted to Pediatric Intensive Care Units of Holy Family Hospital (HFH), Rawalpindi and Benazir Bhutto Hospital (BBH), Rawalpindi. Methods: In this des...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2018-11-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/966 |
| _version_ | 1818807205528338432 |
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| author | Chaudhary Ehtsham Azmat Abdul Basit Shah Vardag Rabia Anjum Ahmed Moosa Kazi Faraz Iftikhar Mohammad Ammad-Ud-Din Hamzah Saleem |
| author_facet | Chaudhary Ehtsham Azmat Abdul Basit Shah Vardag Rabia Anjum Ahmed Moosa Kazi Faraz Iftikhar Mohammad Ammad-Ud-Din Hamzah Saleem |
| author_sort | Chaudhary Ehtsham Azmat |
| collection | DOAJ |
| description | Objective: This study was conducted to assess the frequency of different microbial isolates and their antibiotic resistance pattern in patients admitted to Pediatric Intensive Care Units of Holy Family Hospital (HFH), Rawalpindi and Benazir Bhutto Hospital (BBH), Rawalpindi.
Methods: In this descriptive cross-sectional study, samples drawn from 253 pediatric patients of Intensive Care Units were included. Data was taken from records of the Pathology Department of the concerned hospitals, from September 2016 to July 2017. Data was collected about the types of specimens, culture positive microbes, and the antibiotic sensitivity of the bacterial isolates.
Results: Amongst the cultures included, 64.8% showed no growth while 32% showed bacterial growth and 3.2% showed fungal growth. Most frequently isolated organism was Escherichia Coli (22.7%) followed by Klebsiella pneumoniae (18.8%), Acinetobacter baumannii (16.8%), Staphylococcus Aureus (10.9%), Pseudomonas (9.9%), Candida (7.9%). The most common pathogen isolated from the respiratory tract was Klebsiella (38.7%); from urinary tract, E.coli (63.2%); from blood, Staphylococcus Aureus (30%). Antibiotic sensitivity showed that the isolated pathogens were most susceptible to Meropenem. It was however less effective against Acinetobacter. Vancomycin was also effective against majority of microbes isolated except for Klebsiella. Fosfomycin showed mixed results.
Conclusion: In Paediatric ICU most commonly isolated pathogens are E.coli, Klebsiella, Acinetobacter and S.aureus. Meropenam and Vancomycin combination is the best guess empiric antibiotic keeping in mind antibiotic sensitivity patteren of these microrganisms. |
| first_indexed | 2024-12-18T19:21:58Z |
| format | Article |
| id | doaj.art-0ad1be9722cc479fb3c9f37efc179765 |
| institution | Directory Open Access Journal |
| issn | 1683-3562 1683-3570 |
| language | English |
| last_indexed | 2024-12-18T19:21:58Z |
| publishDate | 2018-11-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj.art-0ad1be9722cc479fb3c9f37efc1797652022-12-21T20:55:58ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702018-11-0121S-1Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit ExperienceChaudhary Ehtsham Azmat0Abdul Basit Shah Vardag1Rabia Anjum2Ahmed Moosa Kazi3Faraz Iftikhar4Mohammad Ammad-Ud-Din5Hamzah Saleem6Final Year Medical Student Rawalpindi Medical UniversityFinal Year Medical Student Rawalpindi Medical UniversityConsultant Pathologist, Benazir Bhutto Hospital and Rawalpindi Medical UniversityFinal Year Medical Student Rawalpindi Medical UniversityFinal Year Medical Student Rawalpindi Medical UniversityFinal Year Medical Student Rawalpindi Medical UniversityFinal Year Medical Student Rawalpindi Medical UniversityObjective: This study was conducted to assess the frequency of different microbial isolates and their antibiotic resistance pattern in patients admitted to Pediatric Intensive Care Units of Holy Family Hospital (HFH), Rawalpindi and Benazir Bhutto Hospital (BBH), Rawalpindi. Methods: In this descriptive cross-sectional study, samples drawn from 253 pediatric patients of Intensive Care Units were included. Data was taken from records of the Pathology Department of the concerned hospitals, from September 2016 to July 2017. Data was collected about the types of specimens, culture positive microbes, and the antibiotic sensitivity of the bacterial isolates. Results: Amongst the cultures included, 64.8% showed no growth while 32% showed bacterial growth and 3.2% showed fungal growth. Most frequently isolated organism was Escherichia Coli (22.7%) followed by Klebsiella pneumoniae (18.8%), Acinetobacter baumannii (16.8%), Staphylococcus Aureus (10.9%), Pseudomonas (9.9%), Candida (7.9%). The most common pathogen isolated from the respiratory tract was Klebsiella (38.7%); from urinary tract, E.coli (63.2%); from blood, Staphylococcus Aureus (30%). Antibiotic sensitivity showed that the isolated pathogens were most susceptible to Meropenem. It was however less effective against Acinetobacter. Vancomycin was also effective against majority of microbes isolated except for Klebsiella. Fosfomycin showed mixed results. Conclusion: In Paediatric ICU most commonly isolated pathogens are E.coli, Klebsiella, Acinetobacter and S.aureus. Meropenam and Vancomycin combination is the best guess empiric antibiotic keeping in mind antibiotic sensitivity patteren of these microrganisms.https://www.journalrmc.com/index.php/JRMC/article/view/966Microbial IsolatesAntibiotic Sensitivity |
| spellingShingle | Chaudhary Ehtsham Azmat Abdul Basit Shah Vardag Rabia Anjum Ahmed Moosa Kazi Faraz Iftikhar Mohammad Ammad-Ud-Din Hamzah Saleem Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit Experience Journal of Rawalpindi Medical College Microbial Isolates Antibiotic Sensitivity |
| title | Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit Experience |
| title_full | Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit Experience |
| title_fullStr | Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit Experience |
| title_full_unstemmed | Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit Experience |
| title_short | Microbial Isolates and their Antibiotic Resistance Pattern; Pediatric Intensive Care Unit Experience |
| title_sort | microbial isolates and their antibiotic resistance pattern pediatric intensive care unit experience |
| topic | Microbial Isolates Antibiotic Sensitivity |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/966 |
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