Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012
Evidence accumulating in 2011–2012 indicates that there is significant intra- and inter-species transmission of influenza A viruses at agricultural fairs, which has renewed interest in this unique human/swine interface. Six human cases of influenza A (H3N2) variant (H3N2v) virus infections were epid...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2012-07-01
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| Series: | Emerging Microbes and Infections |
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| Online Access: | https://www.tandfonline.com/doi/10.1038/emi.2012.33 |
| _version_ | 1797661225961652224 |
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| author | Andrew S Bowman Srinand Sreevatsan Mary L Killian Shannon L Page Sarah W Nelson Jacqueline M Nolting Carol Cardona Richard D Slemons |
| author_facet | Andrew S Bowman Srinand Sreevatsan Mary L Killian Shannon L Page Sarah W Nelson Jacqueline M Nolting Carol Cardona Richard D Slemons |
| author_sort | Andrew S Bowman |
| collection | DOAJ |
| description | Evidence accumulating in 2011–2012 indicates that there is significant intra- and inter-species transmission of influenza A viruses at agricultural fairs, which has renewed interest in this unique human/swine interface. Six human cases of influenza A (H3N2) variant (H3N2v) virus infections were epidemiologically linked to swine exposure at fairs in the United States in 2011. In 2012, the number of H3N2v cases in the Midwest had exceeded 300 from early July to September, 2012. Prospective influenza A virus surveillance among pigs at Ohio fairs resulted in the detection of H3N2pM (H3N2 influenza A viruses containing the matrix (M) gene from the influenza A (H1N1) pdm09 virus). These H3N2pM viruses were temporally and spatially linked to several human H3N2v cases. Complete genomic analyses of these H3N2pM isolates demonstrated >99% nucleotide similarity to the H3N2v isolates recovered from human cases. Actions to mitigate the bidirectional interspecies transmission of influenza A virus between people and animals at agricultural fairs may be warranted.Emerging Microbes & Infections (2012) 1, e33; doi:10.1038/emi.2012.33 |
| first_indexed | 2024-03-11T18:42:19Z |
| format | Article |
| id | doaj.art-0ad38b431407405d80b404caee827705 |
| institution | Directory Open Access Journal |
| issn | 2222-1751 |
| language | English |
| last_indexed | 2024-03-11T18:42:19Z |
| publishDate | 2012-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj.art-0ad38b431407405d80b404caee8277052023-10-12T10:27:59ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512012-07-01111810.1038/emi.2012.33Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012Andrew S Bowman0Srinand Sreevatsan1Mary L Killian2Shannon L Page3Sarah W Nelson4Jacqueline M Nolting5Carol Cardona6Richard D Slemons7Department of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USADepartments of Veterinary Biomedical Sciences and Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 5108, USADiagnostic Virology Laboratory, National Veterinary Services Laboratories, United States Department of Agriculture, Animal and Plant Health Inspection Service, Ames, IA 50010, USAOhio Department of Health, Columbus, OH 43215, USADepartment of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USADepartment of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USADepartments of Veterinary Biomedical Sciences and Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 5108, USADepartment of Veterinary Preventive Medicine, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210, USAEvidence accumulating in 2011–2012 indicates that there is significant intra- and inter-species transmission of influenza A viruses at agricultural fairs, which has renewed interest in this unique human/swine interface. Six human cases of influenza A (H3N2) variant (H3N2v) virus infections were epidemiologically linked to swine exposure at fairs in the United States in 2011. In 2012, the number of H3N2v cases in the Midwest had exceeded 300 from early July to September, 2012. Prospective influenza A virus surveillance among pigs at Ohio fairs resulted in the detection of H3N2pM (H3N2 influenza A viruses containing the matrix (M) gene from the influenza A (H1N1) pdm09 virus). These H3N2pM viruses were temporally and spatially linked to several human H3N2v cases. Complete genomic analyses of these H3N2pM isolates demonstrated >99% nucleotide similarity to the H3N2v isolates recovered from human cases. Actions to mitigate the bidirectional interspecies transmission of influenza A virus between people and animals at agricultural fairs may be warranted.Emerging Microbes & Infections (2012) 1, e33; doi:10.1038/emi.2012.33https://www.tandfonline.com/doi/10.1038/emi.2012.33human H3N2vH3N2pMinfluenzafairswine |
| spellingShingle | Andrew S Bowman Srinand Sreevatsan Mary L Killian Shannon L Page Sarah W Nelson Jacqueline M Nolting Carol Cardona Richard D Slemons Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012 Emerging Microbes and Infections human H3N2v H3N2pM influenza fair swine |
| title | Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012 |
| title_full | Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012 |
| title_fullStr | Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012 |
| title_full_unstemmed | Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012 |
| title_short | Molecular evidence for interspecies transmission of H3N2pM/H3N2v influenza A viruses at an Ohio agricultural fair, July 2012 |
| title_sort | molecular evidence for interspecies transmission of h3n2pm h3n2v influenza a viruses at an ohio agricultural fair july 2012 |
| topic | human H3N2v H3N2pM influenza fair swine |
| url | https://www.tandfonline.com/doi/10.1038/emi.2012.33 |
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