| Summary: | Background. The purpose of the research is to improve the pathological diagnosis
of acute destructive pancreatitis. Materials and methods. To solve the purpose, we have
developed new tactical and technical methods of pathological examination of a corpse in
acute destructive pancreatitis. Before the autopsy, a thorough study of the medical documentation
is carried out, and the autopsy itself involves the study of organopathology, including
at the light-optical level. This is necessary for understanding the mechanisms of
thanatogenesis and establishing the immediate cause of the patient’s death. The autopsy
technique is fraught with certain difficulties, since many of the subjects underwent surgical
interventions during their lifetime. In this case, the pathological process covers the near and
distant tissue structures. For a pathologist, it is important to understand the sequence of inclusion
of other internal organs in the purulent-necrotic process. Results. The results of
postmortem examination are presented. The main tactical and technical aspects were
worked out on 65 corpses. In acute destructive pancreatitis, the introduction of a contrast
agent into the duct system of the pancreas gives an idea of the ways in which the purulentnecrotic
process spreads along the retroperitoneal tissue and other anatomical structures.
The use of the device developed by the authors makes it possible to more accurately bring
the contrast agent to the epicenter of the pathologically altered cellular structures of the retroperitoneal
space, to predetermine the volume of the lesion and the pathway of fluid outflow.
The variants of the dissemination of the purulent-necrotic process were studied, on
the basis of which the types of acute destructive pancreatitis were proposed. Conclusion.
The developed set of tactical and technical methods of pathological anatomical examination
during the section of organs allows one to arrive at a qualitative clinical and anatomical
analysis of the case in acute destructive pancreatitis.
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