The BvgAS Regulon of <italic toggle="yes">Bordetella pertussis</italic>

The BvgAS Regulon of <italic toggle="yes">Bordetella pertussis</italic>

ABSTRACT Nearly all virulence factors in Bordetella pertussis are activated by a master two-component system, BvgAS, composed of the sensor kinase BvgS and the response regulator BvgA. When BvgS is active, BvgA is phosphorylated (BvgA~P), and virulence-activated genes (vags) are expressed [Bvg(+) mo...

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Bibliographic Details
Main Authors: Kyung Moon, Richard P. Bonocora, David D. Kim, Qing Chen, Joseph T. Wade, Scott Stibitz, Deborah M. Hinton
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Subjects:
BvgAS regulon
RNA polymerase
RNA-seq
brpL
pertussis
Online Access:https://journals.asm.org/doi/10.1128/mBio.01526-17

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