Thiamine as adjunctive therapy for diabetic ketoacidosis (DKAT) trial protocol and statistical analysis plan: a prospective, single-centre, double-blind, randomised, placebo-controlled clinical trial in the USA

Thiamine as adjunctive therapy for diabetic ketoacidosis (DKAT) trial protocol and statistical analysis plan: a prospective, single-centre, double-blind, randomised, placebo-controlled clinical trial in the USA

Introduction Diabetic ketoacidosis (DKA) is a potentially life-threatening diabetic complication. Despite the high prevalence of DKA and the substantial associated healthcare burden, limited research on strategies to improve outcomes currently exists.Thiamine (vitamin B1) is a cofactor of pyruvate d...

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Bibliographic Details
Main Authors: Ari Moskowitz, Michael W Donnino, Anne V Grossestreuer, Katherine M Berg, Long Ngo, Xiaowen Liu, Jacob Vine, Shivani Mehta, Lakshman Balaji, Noa Berlin, Meredith Shea
Format: Article
Language:English
Published: BMJ Publishing Group 2024-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/2/e077586.full

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https://bmjopen.bmj.com/content/14/2/e077586.full

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