Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case report
Purpose: To describe an unusual case of metastatic gastric adenocarcinoma involving the eyelids and anterior orbit. Observations: An 82-year-old female with prior diagnosis of locally metastatic gastric adenocarcinoma developed eyelid edema. Initial ophthalmic assessment suggested presence of a chal...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993623000221 |
| _version_ | 1797904260992598016 |
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| author | Nicole P. Rebollo Gabrielle A. Yeaney Catherine J. Hwang Julian D. Perry |
| author_facet | Nicole P. Rebollo Gabrielle A. Yeaney Catherine J. Hwang Julian D. Perry |
| author_sort | Nicole P. Rebollo |
| collection | DOAJ |
| description | Purpose: To describe an unusual case of metastatic gastric adenocarcinoma involving the eyelids and anterior orbit. Observations: An 82-year-old female with prior diagnosis of locally metastatic gastric adenocarcinoma developed eyelid edema. Initial ophthalmic assessment suggested presence of a chalazion that did not resolve with medical management. A few weeks after initial evaluation, the eyelid and facial edema worsened. Eyelid skin biopsy showed only inflammatory changes, but inflammatory work up was unrevealing and there was poor response to steroid therapy. Orbitotomy with biopsy ultimately revealed involvement of eyelid skin by a signet ring cell metastatic gastric carcinoma. Conclusions and importance: Eyelid and orbital metastasis from gastric adenocarcinoma may present mainly with inflammatory signs and symptoms masquerading as a chalazion. This case highlights the spectrum of presentation of this rare periocular metastasis. |
| first_indexed | 2024-04-10T09:46:04Z |
| format | Article |
| id | doaj.art-0ad7dccda4ef4c2e92058fb76eb60b58 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-04-10T09:46:04Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-0ad7dccda4ef4c2e92058fb76eb60b582023-02-17T04:55:18ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362023-03-0129101814Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case reportNicole P. Rebollo0Gabrielle A. Yeaney1Catherine J. Hwang2Julian D. Perry3Cleveland Clinic, Cole Eye Institute, 9500 Euclid Ave, Cleveland, OH, 44195, USA; Corresponding author. 9500 Euclid Ave, Cleveland, OH, USA.Cleveland Clinic, Division of Ocular Pathology and Neuropathology, 9410 Carnegie Ave, Cleveland, OH, 44106, USACleveland Clinic, Cole Eye Institute, 9500 Euclid Ave, Cleveland, OH, 44195, USACleveland Clinic, Cole Eye Institute, 9500 Euclid Ave, Cleveland, OH, 44195, USAPurpose: To describe an unusual case of metastatic gastric adenocarcinoma involving the eyelids and anterior orbit. Observations: An 82-year-old female with prior diagnosis of locally metastatic gastric adenocarcinoma developed eyelid edema. Initial ophthalmic assessment suggested presence of a chalazion that did not resolve with medical management. A few weeks after initial evaluation, the eyelid and facial edema worsened. Eyelid skin biopsy showed only inflammatory changes, but inflammatory work up was unrevealing and there was poor response to steroid therapy. Orbitotomy with biopsy ultimately revealed involvement of eyelid skin by a signet ring cell metastatic gastric carcinoma. Conclusions and importance: Eyelid and orbital metastasis from gastric adenocarcinoma may present mainly with inflammatory signs and symptoms masquerading as a chalazion. This case highlights the spectrum of presentation of this rare periocular metastasis.http://www.sciencedirect.com/science/article/pii/S2451993623000221Eyelid metastasisGastric adenocarcinomaMetastasis masqueraderChalazion |
| spellingShingle | Nicole P. Rebollo Gabrielle A. Yeaney Catherine J. Hwang Julian D. Perry Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case report American Journal of Ophthalmology Case Reports Eyelid metastasis Gastric adenocarcinoma Metastasis masquerader Chalazion |
| title | Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case report |
| title_full | Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case report |
| title_fullStr | Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case report |
| title_full_unstemmed | Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case report |
| title_short | Metastatic gastric carcinoma to the eyelids masquerading as a chalazion: A case report |
| title_sort | metastatic gastric carcinoma to the eyelids masquerading as a chalazion a case report |
| topic | Eyelid metastasis Gastric adenocarcinoma Metastasis masquerader Chalazion |
| url | http://www.sciencedirect.com/science/article/pii/S2451993623000221 |
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