Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei

Cytokinesis in eukaryotes is regulated by a Polo-like kinase-mediated and Aurora B kinase-mediated signalling pathway that promotes the assembly of the actomyosin contractile ring, a cytokinesis machinery conserved across evolution from yeast to humans. Trypanosoma brucei, an early divergent parasit...

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Bibliographic Details
Main Authors: Yasuhiro Kurasawa, Kyu Joon Lee, Huiqing Hu, Kieu T. M. Pham, Ziyin Li
Format: Article
Language:English
Published: The Royal Society 2022-10-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220197