Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei
Cytokinesis in eukaryotes is regulated by a Polo-like kinase-mediated and Aurora B kinase-mediated signalling pathway that promotes the assembly of the actomyosin contractile ring, a cytokinesis machinery conserved across evolution from yeast to humans. Trypanosoma brucei, an early divergent parasit...
Main Authors: | Yasuhiro Kurasawa, Kyu Joon Lee, Huiqing Hu, Kieu T. M. Pham, Ziyin Li |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2022-10-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.220197 |
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