Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons.

Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons.

Chmp2b is closely related to Vps2, a key component of the yeast protein complex that creates the intralumenal vesicles of multivesicular bodies. Dominant negative mutations in Chmp2b cause autophagosome accumulation and neurodegenerative disease. Loss of Chmp2b causes failure of dendritic spine matu...

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Bibliographic Details
Main Authors: Jun Xu, Mariko Nonogaki, Ravi Madhira, Hsiao-Yen Ma, Ola Hermanson, Chrissa Kioussi, Michael K Gross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528757?pdf=render

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