Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review
β-Glucan exhibits many biological activities and functions such as stimulation of the immune system and anti-inflammatory, anti-microbial, anti-infective, anti-viral, anti-tumor, anti-oxidant, anti-coagulant, cholesterol-lowering, radio protective, and wound healing effects. It has a wide v...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-12-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/1/57 |
| _version_ | 1818354322961858560 |
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| author | Hongjie Yuan Ping Lan Yan He Chengliang Li Xia Ma |
| author_facet | Hongjie Yuan Ping Lan Yan He Chengliang Li Xia Ma |
| author_sort | Hongjie Yuan |
| collection | DOAJ |
| description | β-Glucan exhibits many biological activities and functions such as stimulation of the immune system and anti-inflammatory, anti-microbial, anti-infective, anti-viral, anti-tumor, anti-oxidant, anti-coagulant, cholesterol-lowering, radio protective, and wound healing effects. It has a wide variety of uses in pharmaceutical, cosmetic, and chemical industries as well as in food processing units. However, due to its dense triple helix structure, formed by the interaction of polyhydroxy groups in the β-<span style="font-variant: small-caps;">d</span>-glucan molecule, it features poor solubility, which not only constrains its applications, but also inhibits its physiological function in vivo. One aim is to expand the applications for modified β-glucan with potential to prevent disease, various therapeutic purposes and as health-improving ingredients in functional foods and cosmetics. This review introduces the major modification methods required to understand the bioactivity of β-glucan and critically provides a literature survey on the structural features of this molecule and reported biological activity. We also discuss a new method to create novel opportunities to exploit maximally various properties of β-glucan, namely ultrasound-assisted enzymatic modification. |
| first_indexed | 2024-12-13T19:23:35Z |
| format | Article |
| id | doaj.art-0adcdab342ff423995c69d462efbd463 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T19:23:35Z |
| publishDate | 2019-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-0adcdab342ff423995c69d462efbd4632022-12-21T23:34:06ZengMDPI AGMolecules1420-30492019-12-012515710.3390/molecules25010057molecules25010057Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical ReviewHongjie Yuan0Ping Lan1Yan He2Chengliang Li3Xia Ma4School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, ChinaGuangxi Key Laboratory of Polysaccharide Materials and Modification, School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530008, ChinaSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, ChinaLB Cosmeceutical Technology Co., Ltd., Shanghai 201499, ChinaSchool of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai 201418, Chinaβ-Glucan exhibits many biological activities and functions such as stimulation of the immune system and anti-inflammatory, anti-microbial, anti-infective, anti-viral, anti-tumor, anti-oxidant, anti-coagulant, cholesterol-lowering, radio protective, and wound healing effects. It has a wide variety of uses in pharmaceutical, cosmetic, and chemical industries as well as in food processing units. However, due to its dense triple helix structure, formed by the interaction of polyhydroxy groups in the β-<span style="font-variant: small-caps;">d</span>-glucan molecule, it features poor solubility, which not only constrains its applications, but also inhibits its physiological function in vivo. One aim is to expand the applications for modified β-glucan with potential to prevent disease, various therapeutic purposes and as health-improving ingredients in functional foods and cosmetics. This review introduces the major modification methods required to understand the bioactivity of β-glucan and critically provides a literature survey on the structural features of this molecule and reported biological activity. We also discuss a new method to create novel opportunities to exploit maximally various properties of β-glucan, namely ultrasound-assisted enzymatic modification.https://www.mdpi.com/1420-3049/25/1/57polysaccharidesβ-glucansolublebiological activitymodificationanti-oxidationfunctions |
| spellingShingle | Hongjie Yuan Ping Lan Yan He Chengliang Li Xia Ma Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review Molecules polysaccharides β-glucan soluble biological activity modification anti-oxidation functions |
| title | Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review |
| title_full | Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review |
| title_fullStr | Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review |
| title_full_unstemmed | Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review |
| title_short | Effect of the Modifications on the Physicochemical and Biological Properties of β-Glucan—A Critical Review |
| title_sort | effect of the modifications on the physicochemical and biological properties of β glucan a critical review |
| topic | polysaccharides β-glucan soluble biological activity modification anti-oxidation functions |
| url | https://www.mdpi.com/1420-3049/25/1/57 |
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