Novel antibody competition binding assay identifies distinct serological profiles associated with protection

Novel antibody competition binding assay identifies distinct serological profiles associated with protection

IntroductionPre-erythrocytic malaria vaccines hold the promise of inducing sterile protection thereby preventing the morbidity and mortality associated with Plasmodium infection. The main surface antigen of P. falciparum sporozoites, i.e., the circumsporozoite protein (CSP), has been extensively exp...

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Bibliographic Details
Main Authors:	Jessica S. Bolton, Randall S. MacGill, Emily Locke, Jason A. Regules, Elke S. Bergmann-Leitner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Series:	Frontiers in Immunology
Subjects:	serology circumsporozoite protein antigen-specificity equivalency vaccine protection
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1303446/full

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