Long-term management of pediatric psoriasis with ixekizumab: a case report

Psoriasis in pediatric patients is uncommon and the management of moderate-to-severe cases can be challenging. We report the case of a 17-year-old girl who presented with severe plaque psoriasis unresponsive to UVB phototherapy. The Psoriasis Area Severity Index (PASI) was 18 and the Dermatology Lif...

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Main Authors: Diego Orsini, Luciano Ibba, Alessandra Narcisi, Pasquale Frascione, Alessia Pacifico, Mario Valenti, Antonio Costanzo, Luigi Gargiulo
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2023.2198622
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author Diego Orsini
Luciano Ibba
Alessandra Narcisi
Pasquale Frascione
Alessia Pacifico
Mario Valenti
Antonio Costanzo
Luigi Gargiulo
author_facet Diego Orsini
Luciano Ibba
Alessandra Narcisi
Pasquale Frascione
Alessia Pacifico
Mario Valenti
Antonio Costanzo
Luigi Gargiulo
author_sort Diego Orsini
collection DOAJ
description Psoriasis in pediatric patients is uncommon and the management of moderate-to-severe cases can be challenging. We report the case of a 17-year-old girl who presented with severe plaque psoriasis unresponsive to UVB phototherapy. The Psoriasis Area Severity Index (PASI) was 18 and the Dermatology Life Quality Index was 24. We decided to prescribe ixekizumab, observing complete skin clearance after only 8 weeks. The patient is still on treatment with no reported adverse events after two years.
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spelling doaj.art-0ae622890b6548feb84f0714e135a2102023-09-15T14:28:53ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532023-12-0134110.1080/09546634.2023.21986222198622Long-term management of pediatric psoriasis with ixekizumab: a case reportDiego Orsini0Luciano Ibba1Alessandra Narcisi2Pasquale Frascione3Alessia Pacifico4Mario Valenti5Antonio Costanzo6Luigi Gargiulo7Clinical Dermatology Unit, San Gallicano Dermatological Institute IRCCSDermatology Unit, IRCCS Humanitas Research HospitalDermatology Unit, IRCCS Humanitas Research HospitalUOSD Dermatologia Oncologica, Istituto Dermatologico San Gallicano (IRCCS)Clinical Dermatology Unit, San Gallicano Dermatological Institute IRCCSDermatology Unit, IRCCS Humanitas Research HospitalDermatology Unit, IRCCS Humanitas Research HospitalDermatology Unit, IRCCS Humanitas Research HospitalPsoriasis in pediatric patients is uncommon and the management of moderate-to-severe cases can be challenging. We report the case of a 17-year-old girl who presented with severe plaque psoriasis unresponsive to UVB phototherapy. The Psoriasis Area Severity Index (PASI) was 18 and the Dermatology Life Quality Index was 24. We decided to prescribe ixekizumab, observing complete skin clearance after only 8 weeks. The patient is still on treatment with no reported adverse events after two years.http://dx.doi.org/10.1080/09546634.2023.2198622ixekizumabpediatricpsoriasisreal-life
spellingShingle Diego Orsini
Luciano Ibba
Alessandra Narcisi
Pasquale Frascione
Alessia Pacifico
Mario Valenti
Antonio Costanzo
Luigi Gargiulo
Long-term management of pediatric psoriasis with ixekizumab: a case report
Journal of Dermatological Treatment
ixekizumab
pediatric
psoriasis
real-life
title Long-term management of pediatric psoriasis with ixekizumab: a case report
title_full Long-term management of pediatric psoriasis with ixekizumab: a case report
title_fullStr Long-term management of pediatric psoriasis with ixekizumab: a case report
title_full_unstemmed Long-term management of pediatric psoriasis with ixekizumab: a case report
title_short Long-term management of pediatric psoriasis with ixekizumab: a case report
title_sort long term management of pediatric psoriasis with ixekizumab a case report
topic ixekizumab
pediatric
psoriasis
real-life
url http://dx.doi.org/10.1080/09546634.2023.2198622
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