Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of Drugs
The role of randomized controlled trials (RCTs) and observational studies in evaluation of the efficacy and safety of cardiology drugs is compared in the article. The clear conclusion is made that RCTs are the basis of modern evidence-based medicine, and that they have no alternative. Observational ...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2016-11-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/1338 |
| _version_ | 1826949684456849408 |
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| author | S. Yu. Martsevich N. P. Kutishenko |
| author_facet | S. Yu. Martsevich N. P. Kutishenko |
| author_sort | S. Yu. Martsevich |
| collection | DOAJ |
| description | The role of randomized controlled trials (RCTs) and observational studies in evaluation of the efficacy and safety of cardiology drugs is compared in the article. The clear conclusion is made that RCTs are the basis of modern evidence-based medicine, and that they have no alternative. Observational studies conducted in compliance with the modern rules can be a source of information on the efficacy of drugs only in the absence of data from RCTs. |
| first_indexed | 2024-03-08T14:02:41Z |
| format | Article |
| id | doaj.art-0ae6994988ee4090ad26da7c581b580e |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2025-02-17T22:18:31Z |
| publishDate | 2016-11-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-0ae6994988ee4090ad26da7c581b580e2024-12-04T11:48:12ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-11-0112556757310.20996/1819-6446-2016-12-5-567-5731264Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of DrugsS. Yu. Martsevich0N. P. Kutishenko1State Research Center for Preventive Medicine. Petroverigsky per. 10-3, Moscow, 101990, RussiaState Research Center for Preventive Medicine. Petroverigsky per. 10-3, Moscow, 101990, RussiaThe role of randomized controlled trials (RCTs) and observational studies in evaluation of the efficacy and safety of cardiology drugs is compared in the article. The clear conclusion is made that RCTs are the basis of modern evidence-based medicine, and that they have no alternative. Observational studies conducted in compliance with the modern rules can be a source of information on the efficacy of drugs only in the absence of data from RCTs.https://www.rpcardio.online/jour/article/view/1338randomized controlled trialsobservational studiescomparison of informativeness in evaluation of drug efficacy |
| spellingShingle | S. Yu. Martsevich N. P. Kutishenko Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of Drugs Рациональная фармакотерапия в кардиологии randomized controlled trials observational studies comparison of informativeness in evaluation of drug efficacy |
| title | Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of Drugs |
| title_full | Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of Drugs |
| title_fullStr | Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of Drugs |
| title_full_unstemmed | Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of Drugs |
| title_short | Randomised Clinical Trials and Observational Studies: the Ratio in the Hierarchy of Evidence of the Efficacy of Drugs |
| title_sort | randomised clinical trials and observational studies the ratio in the hierarchy of evidence of the efficacy of drugs |
| topic | randomized controlled trials observational studies comparison of informativeness in evaluation of drug efficacy |
| url | https://www.rpcardio.online/jour/article/view/1338 |
| work_keys_str_mv | AT syumartsevich randomisedclinicaltrialsandobservationalstudiestheratiointhehierarchyofevidenceoftheefficacyofdrugs AT npkutishenko randomisedclinicaltrialsandobservationalstudiestheratiointhehierarchyofevidenceoftheefficacyofdrugs |