Ligand photo-isomerization triggers conformational changes in iGluR2 ligand binding domain.

Ligand photo-isomerization triggers conformational changes in iGluR2 ligand binding domain.

Neurological glutamate receptors bind a variety of artificial ligands, both agonistic and antagonistic, in addition to glutamate. Studying their small molecule binding properties increases our understanding of the central nervous system and a variety of associated pathologies. The large, oligomeric...

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Bibliographic Details
Main Authors:	Tino Wolter, Thomas Steinbrecher, Dirk Trauner, Marcus Elstner
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3979659?pdf=render

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