Roles of Cullin-RING Ubiquitin Ligases in Cardiovascular Diseases

Roles of Cullin-RING Ubiquitin Ligases in Cardiovascular Diseases

Maintenance of protein homeostasis is crucial for virtually every aspect of eukaryotic biology. The ubiquitin-proteasome system (UPS) represents a highly regulated quality control machinery that protects cells from a variety of stress conditions as well as toxic proteins. A large body of evidence ha...

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Bibliographic Details
Main Authors: Stephanie Diaz, Kankan Wang, Benita Sjögren, Xing Liu
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomolecules
Subjects:
ubiquitin E3 ligases
cullin-RING ligases
protein ubiquitination
protein degradation
cardiovascular disease
Online Access:https://www.mdpi.com/2218-273X/12/3/416

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