Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity

Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity

The development of a polarized neuron relies on the selective transport of proteins to axons and dendrites. Although it is well known that the microtubule cytoskeleton has a central role in establishing neuronal polarity, how its specific organization is established and maintained is poorly understo...

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Bibliographic Details
Main Authors: Liu He, Robbelien Kooistra, Ravi Das, Ellen Oudejans, Eric van Leen, Johannes Ziegler, Sybren Portegies, Bart de Haan, Anna van Regteren Altena, Riccardo Stucchi, AF Maarten Altelaar, Stefan Wieser, Michael Krieg, Casper C Hoogenraad, Martin Harterink
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
neuron polarity
microtubule
kinesin
CRMP
Ankyrin
Online Access:https://elifesciences.org/articles/55111

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