Bone morphogenetic protein-induced heterotopic bone formation: What have we learned from the history of a half century?

Bone morphogenetic protein-induced heterotopic bone formation: What have we learned from the history of a half century?

Bone morphogenetic protein (BMP) was originally discovered by Marshall Urist a half century ago following the observation of a unique activity that induced heterotopic bone formation in skeletal muscle tissue. The molecular mechanisms underlying the induction of heterotopic bone formation in skeleta...

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Bibliographic Details
Main Authors: Takenobu Katagiri, PhD, Kenji Osawa, Sho Tsukamoto, Mai Fujimoto, Arei Miyamoto, Takato Mizuta
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Japanese Dental Science Review
Subjects:
Bone formation
BMP
Receptor
Signal transduction
Skeletal muscle
Differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S1882761614000295

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