Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study
Abstract Introduction The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health‐related quality of life (HRQoL) of those who develop the disease. Context‐specific assessment of HRQoL and its associated factors informs the development of contextually appropriat...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-09-01
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| Series: | Endocrinology, Diabetes & Metabolism |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/edm2.353 |
| _version_ | 1811261087172001792 |
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| author | Naomi Carter Jialin Li Miao Xu Li Li Xuelan Fan Shuyan Zhu Pritpal Chahal Kaushik Chattopadhyay |
| author_facet | Naomi Carter Jialin Li Miao Xu Li Li Xuelan Fan Shuyan Zhu Pritpal Chahal Kaushik Chattopadhyay |
| author_sort | Naomi Carter |
| collection | DOAJ |
| description | Abstract Introduction The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health‐related quality of life (HRQoL) of those who develop the disease. Context‐specific assessment of HRQoL and its associated factors informs the development of contextually appropriate interventions to improve HRQoL. This study aimed to determine the HRQoL and its associated factors in people with T2DM at a tertiary care clinic in Ningbo, China. Methods A cross‐sectional survey was undertaken among 406 people with T2DM in 2020–21. The primary outcome was HRQoL measured using EQ VAS and EQ‐5D index from the EQ‐5D‐3L questionnaire. Multivariable regression analysis was used to determine the factors associated with HRQoL scores. Results The mean (± standard deviation) EQ VAS score was 68.7 (13.8). Median (interquartile range) EQ‐5D index was 1 (0.027). Prevalence of problems in HRQoL domains was as follows: pain/discomfort (15.7%), anxiety/depression (13.3%), mobility (5.4%), self‐care (3.5%) and managing usual activities (5.2%). The ≥60 years age group had a mean EQ VAS score 8.7 points higher (95% CI 3.4, 13.9; p < .001) than the 18–39 years age group. Those with T2DM >10 years had a mean EQ VAS score 8.6 points lower than those with a duration <1 year (−12.8, −4.4; p = .001). A T2DM duration >10 years was associated with a reduction in the EQ‐5D index of 0.029 (−0.041, −0.016; p < .001) compared with a duration <1 year. Conclusions Depression/anxiety and pain/discomfort are important domains of reduced HRQoL for this population. A longer duration of T2DM is associated with reduced HRQoL scores, including both EQ VAS and EQ‐5D index. Increasing age may be counterintuitively associated with an increase in EQ VAS score in this population, potentially reflecting a ‘paradox of aging’ process. Future work should focus on developing, evaluating and implementing interventions to improve HRQoL in T2DM, such as strategies to manage pain and mental health conditions. |
| first_indexed | 2024-04-12T18:57:19Z |
| format | Article |
| id | doaj.art-0afb8d99036d44e2811a6495025c4c26 |
| institution | Directory Open Access Journal |
| issn | 2398-9238 |
| language | English |
| last_indexed | 2024-04-12T18:57:19Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Endocrinology, Diabetes & Metabolism |
| spelling | doaj.art-0afb8d99036d44e2811a6495025c4c262022-12-22T03:20:16ZengWileyEndocrinology, Diabetes & Metabolism2398-92382022-09-0155n/an/a10.1002/edm2.353Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional studyNaomi Carter0Jialin Li1Miao Xu2Li Li3Xuelan Fan4Shuyan Zhu5Pritpal Chahal6Kaushik Chattopadhyay7Lifespan and Population Health Academic Unit, School of Medicine University of Nottingham Nottingham UKDepartment of Endocrinology and Metabolism Ningbo First Hospital Ningbo ChinaDepartment of Endocrinology and Metabolism Ningbo First Hospital Ningbo ChinaDepartment of Endocrinology and Metabolism Ningbo First Hospital Ningbo ChinaDepartment of Endocrinology and Metabolism Ningbo First Hospital Ningbo ChinaDepartment of Endocrinology and Metabolism Ningbo First Hospital Ningbo ChinaLifespan and Population Health Academic Unit, School of Medicine University of Nottingham Nottingham UKLifespan and Population Health Academic Unit, School of Medicine University of Nottingham Nottingham UKAbstract Introduction The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health‐related quality of life (HRQoL) of those who develop the disease. Context‐specific assessment of HRQoL and its associated factors informs the development of contextually appropriate interventions to improve HRQoL. This study aimed to determine the HRQoL and its associated factors in people with T2DM at a tertiary care clinic in Ningbo, China. Methods A cross‐sectional survey was undertaken among 406 people with T2DM in 2020–21. The primary outcome was HRQoL measured using EQ VAS and EQ‐5D index from the EQ‐5D‐3L questionnaire. Multivariable regression analysis was used to determine the factors associated with HRQoL scores. Results The mean (± standard deviation) EQ VAS score was 68.7 (13.8). Median (interquartile range) EQ‐5D index was 1 (0.027). Prevalence of problems in HRQoL domains was as follows: pain/discomfort (15.7%), anxiety/depression (13.3%), mobility (5.4%), self‐care (3.5%) and managing usual activities (5.2%). The ≥60 years age group had a mean EQ VAS score 8.7 points higher (95% CI 3.4, 13.9; p < .001) than the 18–39 years age group. Those with T2DM >10 years had a mean EQ VAS score 8.6 points lower than those with a duration <1 year (−12.8, −4.4; p = .001). A T2DM duration >10 years was associated with a reduction in the EQ‐5D index of 0.029 (−0.041, −0.016; p < .001) compared with a duration <1 year. Conclusions Depression/anxiety and pain/discomfort are important domains of reduced HRQoL for this population. A longer duration of T2DM is associated with reduced HRQoL scores, including both EQ VAS and EQ‐5D index. Increasing age may be counterintuitively associated with an increase in EQ VAS score in this population, potentially reflecting a ‘paradox of aging’ process. Future work should focus on developing, evaluating and implementing interventions to improve HRQoL in T2DM, such as strategies to manage pain and mental health conditions.https://doi.org/10.1002/edm2.353diabetes mellitus, type 2quality of lifeChina |
| spellingShingle | Naomi Carter Jialin Li Miao Xu Li Li Xuelan Fan Shuyan Zhu Pritpal Chahal Kaushik Chattopadhyay Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study Endocrinology, Diabetes & Metabolism diabetes mellitus, type 2 quality of life China |
| title | Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study |
| title_full | Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study |
| title_fullStr | Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study |
| title_full_unstemmed | Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study |
| title_short | Health‐related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross‐sectional study |
| title_sort | health related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in ningbo china a cross sectional study |
| topic | diabetes mellitus, type 2 quality of life China |
| url | https://doi.org/10.1002/edm2.353 |
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