Single cell RNA sequencing confirms retinal microglia activation associated with early onset retinal degeneration

Single cell RNA sequencing confirms retinal microglia activation associated with early onset retinal degeneration

Abstract Mutations in the Membrane-type frizzled related protein (Mfrp) gene results in an early-onset retinal degeneration associated with retinitis pigmentosa, microphthalmia, optic disc drusen and foveal schisis. In the current study, a previously characterized mouse model of human retinal degene...

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Bibliographic Details
Main Authors: Asha Kumari, Raul Ayala-Ramirez, Juan Carlos Zenteno, Kristyn Huffman, Roman Sasik, Radha Ayyagari, Shyamanga Borooah
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19351-w

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