Hsp90 inhibition leads to an increase in surface expression of multiple immunological receptors in cancer cells

Hsp90 inhibition leads to an increase in surface expression of multiple immunological receptors in cancer cells

Heat shock protein 90 (Hsp90) is a molecular chaperone important for maintaining protein homeostasis (proteostasis) in the cell. Hsp90 inhibitors are being explored as cancer therapeutics because of their ability to disrupt proteostasis. Inhibiting Hsp90 increases surface density of the immunologica...

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Detaylı Bibliyografya
Asıl Yazarlar: Madison Wickenberg, Rebecca Mercier, Megan Yap, John Walker, Kristi Baker, Paul LaPointe
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2024-04-01
Seri Bilgileri:Frontiers in Molecular Biosciences
Konular:
cancer
chaperones
proteostasis
immunological receptors
HSP90 (heat shock protein 90)
Online Erişim:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1334876/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2024.1334876/full

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