Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report
Medication-related osteonecrosis of the jaw (MRONJ) is a side effect of anti-bone resorption medications. Nowadays antiresorptive medications like bisphosphonate and monoclonal antibodies like denosumab that have been prescribed for bone disorders and metastatic cancer are becoming increasingly com...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-07-01
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| Series: | Case Reports in Clinical Practice |
| Subjects: | |
| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/687 |
| _version_ | 1797742496751550464 |
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| author | Maryam Jalili Sadrabad Elham Saberian |
| author_facet | Maryam Jalili Sadrabad Elham Saberian |
| author_sort | Maryam Jalili Sadrabad |
| collection | DOAJ |
| description |
Medication-related osteonecrosis of the jaw (MRONJ) is a side effect of anti-bone resorption medications. Nowadays antiresorptive medications like bisphosphonate and monoclonal antibodies like denosumab that have been prescribed for bone disorders and metastatic cancer are becoming increasingly common. Although these medications are quite efficient at reducing bone resorption, they can develop osteomyelitis and jaw necrosis as a side effect. A 65-year-old woman was referred to the Oral Medicine Department of Semnan University of Medical Sciences with diffuse bilateral mandibular osteonecrosis, with a history of osteopetrosis and under-treatment of bisphosphonate. This complication started after tooth extraction and without any healing 5 years ago. After 3 sessions of plasma therapy, obvious improvement was seen. A proper medical history and a routine oral examination before treating with any invasive dental treatment are necessary to avoid any medication-related osteonecrosis of the jaw or mucosal abnormalities.
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| first_indexed | 2024-03-12T14:41:40Z |
| format | Article |
| id | doaj.art-0afe5f910a6c4fe78eb33c83163797a5 |
| institution | Directory Open Access Journal |
| issn | 2538-2683 2538-2691 |
| language | English |
| last_indexed | 2024-03-12T14:41:40Z |
| publishDate | 2023-07-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Case Reports in Clinical Practice |
| spelling | doaj.art-0afe5f910a6c4fe78eb33c83163797a52023-08-16T05:57:35ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912023-07-018110.18502/crcp.v8i1.13088Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case ReportMaryam Jalili Sadrabad0Elham Saberian1Oral and Maxillofacial Medicine Department, Dental School, Semnan University of Medical Science, Semnan, Iran.PhD and research student, Pavol Jozef Šafárik University, Klinika Bacikova, Košice, Slovakia. Medication-related osteonecrosis of the jaw (MRONJ) is a side effect of anti-bone resorption medications. Nowadays antiresorptive medications like bisphosphonate and monoclonal antibodies like denosumab that have been prescribed for bone disorders and metastatic cancer are becoming increasingly common. Although these medications are quite efficient at reducing bone resorption, they can develop osteomyelitis and jaw necrosis as a side effect. A 65-year-old woman was referred to the Oral Medicine Department of Semnan University of Medical Sciences with diffuse bilateral mandibular osteonecrosis, with a history of osteopetrosis and under-treatment of bisphosphonate. This complication started after tooth extraction and without any healing 5 years ago. After 3 sessions of plasma therapy, obvious improvement was seen. A proper medical history and a routine oral examination before treating with any invasive dental treatment are necessary to avoid any medication-related osteonecrosis of the jaw or mucosal abnormalities. https://crcp.tums.ac.ir/index.php/crcp/article/view/687OsteonecrosisBisphosphonateOsteopetrosisPlasmaMRONJ |
| spellingShingle | Maryam Jalili Sadrabad Elham Saberian Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report Case Reports in Clinical Practice Osteonecrosis Bisphosphonate Osteopetrosis Plasma MRONJ |
| title | Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report |
| title_full | Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report |
| title_fullStr | Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report |
| title_full_unstemmed | Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report |
| title_short | Plasma Therapy for Medication-Related Osteonecrosis of the Jaws- A Case Report |
| title_sort | plasma therapy for medication related osteonecrosis of the jaws a case report |
| topic | Osteonecrosis Bisphosphonate Osteopetrosis Plasma MRONJ |
| url | https://crcp.tums.ac.ir/index.php/crcp/article/view/687 |
| work_keys_str_mv | AT maryamjalilisadrabad plasmatherapyformedicationrelatedosteonecrosisofthejawsacasereport AT elhamsaberian plasmatherapyformedicationrelatedosteonecrosisofthejawsacasereport |