A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various Cancers

Cancer is a serious and significantly progressive disease. Next to cardiovascular disease, cancer has become the most common cause of mortality in the entire world. Several factors, such as environmental factors, habitual activities, genetic factors, etc., are responsible for cancer. Many cancer pat...

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Main Authors: Hailemeleak Regassa, Anuradha Sourirajan, Vikas Kumar, Sadanand Pandey, Deepak Kumar, Kamal Dev
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/16/3898
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author Hailemeleak Regassa
Anuradha Sourirajan
Vikas Kumar
Sadanand Pandey
Deepak Kumar
Kamal Dev
author_facet Hailemeleak Regassa
Anuradha Sourirajan
Vikas Kumar
Sadanand Pandey
Deepak Kumar
Kamal Dev
author_sort Hailemeleak Regassa
collection DOAJ
description Cancer is a serious and significantly progressive disease. Next to cardiovascular disease, cancer has become the most common cause of mortality in the entire world. Several factors, such as environmental factors, habitual activities, genetic factors, etc., are responsible for cancer. Many cancer patients seek alternative and/or complementary treatments because of the high death rate linked with cancer and the adverse side effects of chemotherapy and radiation therapy. Traditional medicine has a long history that begins with the hunt for botanicals to heal various diseases, including cancer. In the traditional medicinal system, several plants used to treat diseases have many bioactive compounds with curative capability, thereby also helping in disease prevention. Plants also significantly contributed to the modern pharmaceutical industry throughout the world. In the present review, we have listed 33 medicinal plants with active and significant anticancer activity, as well as their anticancer compounds. This article will provide a basic set of information for researchers interested in developing a safe and nontoxic active medicinal plant-based treatment for cancer. The research will give a scientific foundation for the traditional usage of these medicinal herbs to treat cancer.
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spelling doaj.art-0b00d4e98abd4339bc6efe718cee50542023-12-03T13:24:45ZengMDPI AGCancers2072-66942022-08-011416389810.3390/cancers14163898A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various CancersHailemeleak Regassa0Anuradha Sourirajan1Vikas Kumar2Sadanand Pandey3Deepak Kumar4Kamal Dev5Faculty of Applied Sciences & Biotechnology, Shoolini University of Biotechnology & Management Sciences, Solan 173229, IndiaFaculty of Applied Sciences & Biotechnology, Shoolini University of Biotechnology & Management Sciences, Solan 173229, IndiaInstitute of Biotechnology, Chandigarh University, Mohali 140413, IndiaDepartment of Chemistry, College of Natural Sciences, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, KoreaDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, IndiaFaculty of Applied Sciences & Biotechnology, Shoolini University of Biotechnology & Management Sciences, Solan 173229, IndiaCancer is a serious and significantly progressive disease. Next to cardiovascular disease, cancer has become the most common cause of mortality in the entire world. Several factors, such as environmental factors, habitual activities, genetic factors, etc., are responsible for cancer. Many cancer patients seek alternative and/or complementary treatments because of the high death rate linked with cancer and the adverse side effects of chemotherapy and radiation therapy. Traditional medicine has a long history that begins with the hunt for botanicals to heal various diseases, including cancer. In the traditional medicinal system, several plants used to treat diseases have many bioactive compounds with curative capability, thereby also helping in disease prevention. Plants also significantly contributed to the modern pharmaceutical industry throughout the world. In the present review, we have listed 33 medicinal plants with active and significant anticancer activity, as well as their anticancer compounds. This article will provide a basic set of information for researchers interested in developing a safe and nontoxic active medicinal plant-based treatment for cancer. The research will give a scientific foundation for the traditional usage of these medicinal herbs to treat cancer.https://www.mdpi.com/2072-6694/14/16/3898cancermedicinal plantsphytocompoundscytotoxicityimmunotherapiesHimalayas
spellingShingle Hailemeleak Regassa
Anuradha Sourirajan
Vikas Kumar
Sadanand Pandey
Deepak Kumar
Kamal Dev
A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various Cancers
Cancers
cancer
medicinal plants
phytocompounds
cytotoxicity
immunotherapies
Himalayas
title A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various Cancers
title_full A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various Cancers
title_fullStr A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various Cancers
title_full_unstemmed A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various Cancers
title_short A Review of Medicinal Plants of the Himalayas with Anti-Proliferative Activity for the Treatment of Various Cancers
title_sort review of medicinal plants of the himalayas with anti proliferative activity for the treatment of various cancers
topic cancer
medicinal plants
phytocompounds
cytotoxicity
immunotherapies
Himalayas
url https://www.mdpi.com/2072-6694/14/16/3898
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