EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVAL
Purpose: The European Association of Urology (EAU) classifies patients with prostate cancer into three risk groups - low-risk, intermediate- and high-risk depending on the probability of biochemical progression after treatment with curative intent (either radical prostatectomy or radiotherapy). The...
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| Format: | Article |
| Language: | English |
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Peytchinski Publishing
2024-02-01
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| Series: | Journal of IMAB |
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| Online Access: | https://www.journal-imab-bg.org/issues-2024/issue1/2024vol30-issue1-5392-5396.pdf |
| _version_ | 1797292658293473280 |
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| author | Boyan Lazarov |
| author_facet | Boyan Lazarov |
| author_sort | Boyan Lazarov |
| collection | DOAJ |
| description | Purpose: The European Association of Urology (EAU) classifies patients with prostate cancer into three risk groups - low-risk, intermediate- and high-risk depending on the probability of biochemical progression after treatment with curative intent (either radical prostatectomy or radiotherapy). The aim of the present study is to analyze our experience with patients who underwent radical prostatectomy and to look for the relationship between the pathological results from the operation and the distribution of patients into risk groups.
Material/Methods: A single-center, non-interventional study was conducted. The study was performed after analysis of patients undergoing radical prostatectomy (either open or laparoscopic) at the Clinic of Urology in St. Anna Hospital in Varna. The number of patients available for analysis was 201. Data were analyzed with IBM SPSS version 23.
Results: We found that high-risk patients had unfavorable results from the examination of the pathology specimens- patients with pT3a and pT3b were more often from the high-risk group. High-risk patients were also at increased risk of PSA progression and development of distant metastases.
Conclusions: The EAU-risk groups will probably undergo changes connected with the improved methods for the diagnosis of prostate cancer. But still, it is a valid tool which correctly predicts the unfavorable pathology of the removed specimen and also the risk of biochemical progression after radical prostatectomy. |
| first_indexed | 2024-03-07T19:59:39Z |
| format | Article |
| id | doaj.art-0b03da361a9d4efbb232f4bebd7b4629 |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-03-07T19:59:39Z |
| publishDate | 2024-02-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-0b03da361a9d4efbb232f4bebd7b46292024-02-28T09:57:04ZengPeytchinski PublishingJournal of IMAB1312-773X2024-02-013015392539610.5272/jimab.2024301.5392EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVALBoyan Lazarov0https://orcid.org/0000-0002-5167-6022Clinic of Urology, Department of Surgery, Faculty of Medicine, MHAT "Sveta Anna-Varna", Medical University-Varna, Bulgaria.Purpose: The European Association of Urology (EAU) classifies patients with prostate cancer into three risk groups - low-risk, intermediate- and high-risk depending on the probability of biochemical progression after treatment with curative intent (either radical prostatectomy or radiotherapy). The aim of the present study is to analyze our experience with patients who underwent radical prostatectomy and to look for the relationship between the pathological results from the operation and the distribution of patients into risk groups. Material/Methods: A single-center, non-interventional study was conducted. The study was performed after analysis of patients undergoing radical prostatectomy (either open or laparoscopic) at the Clinic of Urology in St. Anna Hospital in Varna. The number of patients available for analysis was 201. Data were analyzed with IBM SPSS version 23. Results: We found that high-risk patients had unfavorable results from the examination of the pathology specimens- patients with pT3a and pT3b were more often from the high-risk group. High-risk patients were also at increased risk of PSA progression and development of distant metastases. Conclusions: The EAU-risk groups will probably undergo changes connected with the improved methods for the diagnosis of prostate cancer. But still, it is a valid tool which correctly predicts the unfavorable pathology of the removed specimen and also the risk of biochemical progression after radical prostatectomy.https://www.journal-imab-bg.org/issues-2024/issue1/2024vol30-issue1-5392-5396.pdfoverall survivalpsa-progressionlymph node metastasesextraprostatic extensionseminal vesicle involvement |
| spellingShingle | Boyan Lazarov EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVAL Journal of IMAB overall survival psa-progression lymph node metastases extraprostatic extension seminal vesicle involvement |
| title | EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVAL |
| title_full | EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVAL |
| title_fullStr | EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVAL |
| title_full_unstemmed | EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVAL |
| title_short | EAU RISK GROUPS APPLIED ON PATIENTS TREATED WITH RADICAL PROSTATECTOMY - ANALYSIS OF PATHOLOGY SPECIMENS AND PATIENT SURVIVAL |
| title_sort | eau risk groups applied on patients treated with radical prostatectomy analysis of pathology specimens and patient survival |
| topic | overall survival psa-progression lymph node metastases extraprostatic extension seminal vesicle involvement |
| url | https://www.journal-imab-bg.org/issues-2024/issue1/2024vol30-issue1-5392-5396.pdf |
| work_keys_str_mv | AT boyanlazarov eauriskgroupsappliedonpatientstreatedwithradicalprostatectomyanalysisofpathologyspecimensandpatientsurvival |