Ethnomedicinal Uses, Phytochemistry and Pharmacological Properties of <i>Suregada</i> Genus: A Review

Plants of the <i>Suregada</i> Roxb. ex Rottler (formerly <i>Gelonium</i> Roxb. ex Willd) are utilized to treat various ailments, namely, hepatic, gum diseases, pyrexia, eczema, and venereal diseases. This review links the reported compounds to ethnomedicinal uses through phar...

Full description

Bibliographic Details
Main Authors: Mandisa Mangisa, Douglas Kemboi, Gerda Fouche, Rudzani Nthambeleni, Moses Kiprotich Langat, Clemence Tarirai, Martin Cheek, Odwa Gonyela, Vuyelwa Jacqueline Tembu
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/10/1390
Description
Summary:Plants of the <i>Suregada</i> Roxb. ex Rottler (formerly <i>Gelonium</i> Roxb. ex Willd) are utilized to treat various ailments, namely, hepatic, gum diseases, pyrexia, eczema, and venereal diseases. This review links the reported compounds to ethnomedicinal uses through pharmacological activities. The compounds possess anticancer, anti-allergic, antibacterial, anti-inflammatory, antioxidant, and anti-HIV properties. From the previous reports, 32 known species of the <i>Suregada</i> genus have been investigated morphologically, and nine were investigated for their phytochemistry and pharmacology. Phytochemistry, ethnomedicinal, and pharmacological uses of the other 23 <i>Suregada</i> species are not known and/or not reported. In this review, abietane diterpenoids are the main compounds expressed by the <i>Suregada</i>, accounting for 71 of the 114 reported compounds. Ten triterpenoids and sterols, one aliphatic, two lignans, five flavonoids, and twenty-one nitrogen-containing compounds have been reported from the genus.
ISSN:1424-8247