Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male Infant
Background: Food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated food allergy in which digestive symptoms such as severe vomiting and diarrhea are induced by cow's milk and/or soy protein in infants. Generally, a food-specific IgE is not detected, and FPIES may be caus...
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| Format: | Article |
| Language: | English |
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Elsevier
2007-01-01
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| Series: | Allergology International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015308972 |
| _version_ | 1819260025570328576 |
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| author | Tomoyuki Kabuki Kosuke Joh |
| author_facet | Tomoyuki Kabuki Kosuke Joh |
| author_sort | Tomoyuki Kabuki |
| collection | DOAJ |
| description | Background: Food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated food allergy in which digestive symptoms such as severe vomiting and diarrhea are induced by cow's milk and/or soy protein in infants. Generally, a food-specific IgE is not detected, and FPIES may be caused by inadvertent exposure to allergenic foods.
Case Summary: The patient in our case was a male infant in whom vomiting had been induced by ingestion of a cow's milk-based formula and bloody diarrhea had been caused by ingestion of breast milk during the neonatal period. Accidental ingestion of a new and extensively hydrolyzed casein/whey formula, MA-mi, caused watery diarrhea at 8 months of age, and FPIES was diagnosed based on these symptoms. In antigen-specific lymphocyte stimulation tests, New MA-1 was negative, but MA-mi and cow's milk antigens were positive. The only causative antigens were derived from cow's milk, and the symptoms were not induced by another extensively hydrolyzed casein formula, New MA-1. The patient grew and developed normally thereafter, and no symptoms were induced by solid food during the course of the condition.
Discussion: MA-mi is likely to be used increasingly for allergic infants, but it is not necessarily a substitute for other hydrolyzed milk formulae in all cases, and care should be taken regarding its use and possible misuse. |
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| format | Article |
| id | doaj.art-0b04fe2ccdb741809fbe53500da6c933 |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-12-23T19:19:21Z |
| publishDate | 2007-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-0b04fe2ccdb741809fbe53500da6c9332022-12-21T17:34:12ZengElsevierAllergology International1323-89302007-01-0156447347610.2332/allergolint.C-06-48Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male InfantTomoyuki Kabuki0Kosuke Joh1Division of Infectious Diseases, Immunology and Allergy, Saitama Children’s Medical Center, Saitama, Japan.Division of Infectious Diseases, Immunology and Allergy, Saitama Children’s Medical Center, Saitama, Japan.Background: Food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated food allergy in which digestive symptoms such as severe vomiting and diarrhea are induced by cow's milk and/or soy protein in infants. Generally, a food-specific IgE is not detected, and FPIES may be caused by inadvertent exposure to allergenic foods. Case Summary: The patient in our case was a male infant in whom vomiting had been induced by ingestion of a cow's milk-based formula and bloody diarrhea had been caused by ingestion of breast milk during the neonatal period. Accidental ingestion of a new and extensively hydrolyzed casein/whey formula, MA-mi, caused watery diarrhea at 8 months of age, and FPIES was diagnosed based on these symptoms. In antigen-specific lymphocyte stimulation tests, New MA-1 was negative, but MA-mi and cow's milk antigens were positive. The only causative antigens were derived from cow's milk, and the symptoms were not induced by another extensively hydrolyzed casein formula, New MA-1. The patient grew and developed normally thereafter, and no symptoms were induced by solid food during the course of the condition. Discussion: MA-mi is likely to be used increasingly for allergic infants, but it is not necessarily a substitute for other hydrolyzed milk formulae in all cases, and care should be taken regarding its use and possible misuse.http://www.sciencedirect.com/science/article/pii/S1323893015308972cow’s milkfood allergyfood protein-induced enterocolitis syndrome |
| spellingShingle | Tomoyuki Kabuki Kosuke Joh Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male Infant Allergology International cow’s milk food allergy food protein-induced enterocolitis syndrome |
| title | Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male Infant |
| title_full | Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male Infant |
| title_fullStr | Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male Infant |
| title_full_unstemmed | Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male Infant |
| title_short | Extensively Hydrolyzed Formula (MA-mi) Induced Exacerbation of Food Protein-Induced Enterocolitis Syndrome (FPIES) in a Male Infant |
| title_sort | extensively hydrolyzed formula ma mi induced exacerbation of food protein induced enterocolitis syndrome fpies in a male infant |
| topic | cow’s milk food allergy food protein-induced enterocolitis syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S1323893015308972 |
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