Induced pluripotent stem cells: Challenges and opportunities for cancer immunotherapy

Induced pluripotent stem cells: Challenges and opportunities for cancer immunotherapy

Despite recent advances in cancer treatment over the past 30 years, therapeutic options remain limited and do not always offer a cure for malignancy. Given that tumour associated antigens (TAA) are, by definition, self-proteins, the need to productively engage autoreactive T cells remains at the he...

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Bibliographic Details
Main Authors: Patty eSachamitr, Simon eHackett, Paul Jonathan Fairchild
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Immunology
Subjects:
Dendritic Cells
Immunotherapy
Cancer
NK cells
Cytotoxic T Cells
iPS cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00176/full

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