Effect of astrocyte GPER on the optic nerve inflammatory response following optic nerve injury in mice

Effect of astrocyte GPER on the optic nerve inflammatory response following optic nerve injury in mice

Activated astrocytes are a primary source of inflammatory factors following traumatic optic neuropathy (TON). Accumulation of inflammatory factors in this context leads to increased axonal damage and loss of retinal ganglion cells (RGCs). Therefore, in the present study, we explored the role of the...

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Bibliographic Details
Main Authors: Xuan Wang, Jiaxing Zhou, Yuwen Wang, Xue Li, Qiumei Hu, Linlin Luo, Xuemei Liu, Wei Liu, Jian Ye
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Astrocytes
Glial cells
Central nervous system
Optic nerve injury
Neuropathy
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024054598

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