Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular Carcinoma

Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a major global malignancy, responsible for >90% of primary liver cancers. Currently available therapeutic options have poor performances due to the highly heterogeneous nature of the tumor cells; recurrence is highly probable, and some patients develop resist...

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Bibliographic Details
Main Authors: Kenya Kamimura, Takeshi Yokoo, Hiroyuki Abe, Norihiro Sakai, Takuro Nagoya, Yuji Kobayashi, Masato Ohtsuka, Hiromi Miura, Akira Sakamaki, Hiroteru Kamimura, Norio Miyamura, Hiroshi Nishina, Shuji Terai
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
hepatocellular carcinoma
gene therapy
diphtheria toxin fragment a
hydrodynamic gene delivery
alpha-fetoprotein
Online Access:https://www.mdpi.com/2072-6694/12/2/472

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https://www.mdpi.com/2072-6694/12/2/472

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