Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

A series of 5-methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones has been designed, synthesized, and characterized by spectral data. Target compounds were screened for their antimicrobial activity against some pathogenic bacteria and fungi, and most of them showed...

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Autors principals: Andrii Lozynskyi, Yulian Konechnyi, Julia Senkiv, Ihor Yushyn, Dmytro Khyluk, Olexandr Karpenko, Yulia Shepeta, Roman Lesyk
Format: Article
Idioma:English
Publicat: MDPI AG 2021-11-01
Col·lecció:Scientia Pharmaceutica
Matèries:
thiazolo[4,5-<i>b</i>]pyridines
antimicrobial activity
pharmacokinetics prediction
molecular docking
Accés en línia:https://www.mdpi.com/2218-0532/89/4/52

Internet

https://www.mdpi.com/2218-0532/89/4/52

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