Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

A series of 5-methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones has been designed, synthesized, and characterized by spectral data. Target compounds were screened for their antimicrobial activity against some pathogenic bacteria and fungi, and most of them showed...

Description complète

Détails bibliographiques
Auteurs principaux: Andrii Lozynskyi, Yulian Konechnyi, Julia Senkiv, Ihor Yushyn, Dmytro Khyluk, Olexandr Karpenko, Yulia Shepeta, Roman Lesyk
Format: Article
Langue:English
Publié: MDPI AG 2021-11-01
Collection:Scientia Pharmaceutica
Sujets:
thiazolo[4,5-<i>b</i>]pyridines
antimicrobial activity
pharmacokinetics prediction
molecular docking
Accès en ligne:https://www.mdpi.com/2218-0532/89/4/52

Internet

https://www.mdpi.com/2218-0532/89/4/52

Documents similaires