Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

A series of 5-methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones has been designed, synthesized, and characterized by spectral data. Target compounds were screened for their antimicrobial activity against some pathogenic bacteria and fungi, and most of them showed...

ver descrição completa

Detalhes bibliográficos
Main Authors: Andrii Lozynskyi, Yulian Konechnyi, Julia Senkiv, Ihor Yushyn, Dmytro Khyluk, Olexandr Karpenko, Yulia Shepeta, Roman Lesyk
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2021-11-01
Colecção:Scientia Pharmaceutica
Assuntos:
thiazolo[4,5-<i>b</i>]pyridines
antimicrobial activity
pharmacokinetics prediction
molecular docking
Acesso em linha:https://www.mdpi.com/2218-0532/89/4/52

Internet

https://www.mdpi.com/2218-0532/89/4/52

Registos relacionados