Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

A series of 5-methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones has been designed, synthesized, and characterized by spectral data. Target compounds were screened for their antimicrobial activity against some pathogenic bacteria and fungi, and most of them showed...

Полное описание

Библиографические подробности
Главные авторы: Andrii Lozynskyi, Yulian Konechnyi, Julia Senkiv, Ihor Yushyn, Dmytro Khyluk, Olexandr Karpenko, Yulia Shepeta, Roman Lesyk
Формат: Статья
Язык:English
Опубликовано: MDPI AG 2021-11-01
Серии:Scientia Pharmaceutica
Предметы:
thiazolo[4,5-<i>b</i>]pyridines
antimicrobial activity
pharmacokinetics prediction
molecular docking
Online-ссылка:https://www.mdpi.com/2218-0532/89/4/52

Internet

https://www.mdpi.com/2218-0532/89/4/52

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