Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

Synthesis and Biological Activity Evaluation of Novel 5-Methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones

A series of 5-methyl-7-phenyl-3<i>H</i>-thiazolo[4,5-<i>b</i>]pyridin-2-ones has been designed, synthesized, and characterized by spectral data. Target compounds were screened for their antimicrobial activity against some pathogenic bacteria and fungi, and most of them showed...

Повний опис

Бібліографічні деталі
Автори: Andrii Lozynskyi, Yulian Konechnyi, Julia Senkiv, Ihor Yushyn, Dmytro Khyluk, Olexandr Karpenko, Yulia Shepeta, Roman Lesyk
Формат: Стаття
Мова:English
Опубліковано: MDPI AG 2021-11-01
Серія:Scientia Pharmaceutica
Предмети:
thiazolo[4,5-<i>b</i>]pyridines
antimicrobial activity
pharmacokinetics prediction
molecular docking
Онлайн доступ:https://www.mdpi.com/2218-0532/89/4/52

Інтернет

https://www.mdpi.com/2218-0532/89/4/52

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