Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal Symptoms

Transdermal systems are attractive methods of drug administration specifically when treating patients for drug addiction. Current systems however are deficient in therapies that allow variable flux values of drug, such as nicotine for smoking cessation or complex dosing regimens using clonidine when...

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Main Authors: Caroline L. Strasinger, Nicole N. Scheff, Ji Wu, Bruce J. Hinds, Audra L. Stinchcomb
Format: Article
Language:English
Published: SAGE Publishing 2009-01-01
Series:Substance Abuse: Research and Treatment
Online Access:https://doi.org/10.4137/SART.S1050
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author Caroline L. Strasinger
Nicole N. Scheff
Ji Wu
Bruce J. Hinds
Audra L. Stinchcomb
author_facet Caroline L. Strasinger
Nicole N. Scheff
Ji Wu
Bruce J. Hinds
Audra L. Stinchcomb
author_sort Caroline L. Strasinger
collection DOAJ
description Transdermal systems are attractive methods of drug administration specifically when treating patients for drug addiction. Current systems however are deficient in therapies that allow variable flux values of drug, such as nicotine for smoking cessation or complex dosing regimens using clonidine when treating opioid withdrawal symptoms. Through the use of functionalized carbon nanotube (CNT) membranes, drug delivery to the skin can be controlled by applying a small electrical bias to create a programmable drug delivery system. Clearly, a transdermal patch system that can be tailored to an individual's needs will increase patient compliance as well as provide much more efficient therapy. The purpose of this paper is to discuss the applicability of using carbon nanotube membranes in transdermal systems for treatment of drug abuse.
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spelling doaj.art-0b0d862fba904decb12e8a205dec9f0c2022-12-21T23:35:00ZengSAGE PublishingSubstance Abuse: Research and Treatment1178-22182009-01-01310.4137/SART.S1050Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal SymptomsCaroline L. Strasinger0Nicole N. Scheff1Ji Wu2Bruce J. Hinds3Audra L. Stinchcomb4Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY, U.S.A.Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY, U.S.A.Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY, U.S.A.Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY, U.S.A.Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY, U.S.A.Transdermal systems are attractive methods of drug administration specifically when treating patients for drug addiction. Current systems however are deficient in therapies that allow variable flux values of drug, such as nicotine for smoking cessation or complex dosing regimens using clonidine when treating opioid withdrawal symptoms. Through the use of functionalized carbon nanotube (CNT) membranes, drug delivery to the skin can be controlled by applying a small electrical bias to create a programmable drug delivery system. Clearly, a transdermal patch system that can be tailored to an individual's needs will increase patient compliance as well as provide much more efficient therapy. The purpose of this paper is to discuss the applicability of using carbon nanotube membranes in transdermal systems for treatment of drug abuse.https://doi.org/10.4137/SART.S1050
spellingShingle Caroline L. Strasinger
Nicole N. Scheff
Ji Wu
Bruce J. Hinds
Audra L. Stinchcomb
Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal Symptoms
Substance Abuse: Research and Treatment
title Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal Symptoms
title_full Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal Symptoms
title_fullStr Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal Symptoms
title_full_unstemmed Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal Symptoms
title_short Carbon Nanotube Membranes for use in the Transdermal Treatment of Nicotine Addiction and Opioid Withdrawal Symptoms
title_sort carbon nanotube membranes for use in the transdermal treatment of nicotine addiction and opioid withdrawal symptoms
url https://doi.org/10.4137/SART.S1050
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