Antigenic Change in Human Influenza A(H2N2) Viruses Detected by Using Human Plasma from Aged and Younger Adult Individuals

Antigenic Change in Human Influenza A(H2N2) Viruses Detected by Using Human Plasma from Aged and Younger Adult Individuals

Human influenza A(H2N2) viruses emerged in 1957 and were replaced by A(H3N2) viruses in 1968. The antigenicity of human H2N2 viruses has been tested by using ferret antisera or mouse and human monoclonal antibodies. Here, we examined the antigenicity of human H2N2 viruses by using human plasma sampl...

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Bibliographic Details
Main Authors: Yukimasa Matsuzawa, Kiyoko Iwatsuki-Horimoto, Yoshinori Nishimoto, Yukiko Abe, Satoshi Fukuyama, Taiki Hamabata, Moe Okuda, Yui Go, Tokiko Watanabe, Masaki Imai, Yasumichi Arai, Ron A.M. Fouchier, Seiya Yamayoshi, Yoshihiro Kawaoka
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Viruses
Subjects:
influenza a virus
aged individuals
h2n2
antigenic drift
antigenic change
Online Access:https://www.mdpi.com/1999-4915/11/11/978

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