Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy Drinking

An otherwise healthy 30-year-old male acquired gastrointestinal beriberi and subsequent Wernicke’s encephalopathy after 1 session of heavy drinking. Nausea, vomiting, and anorexia relentlessly progressed. The patient developed external ophthalmoplegia after 2 months. Intravenous 1,000 mg thiamine re...

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Main Authors: Elysia Tjong, Yen-Yi Peng
Format: Article
Language:English
Published: Karger Publishers 2019-04-01
Series:Case Reports in Neurology
Subjects:
Online Access:https://www.karger.com/Article/FullText/499601
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author Elysia Tjong
Yen-Yi Peng
author_facet Elysia Tjong
Yen-Yi Peng
author_sort Elysia Tjong
collection DOAJ
description An otherwise healthy 30-year-old male acquired gastrointestinal beriberi and subsequent Wernicke’s encephalopathy after 1 session of heavy drinking. Nausea, vomiting, and anorexia relentlessly progressed. The patient developed external ophthalmoplegia after 2 months. Intravenous 1,000 mg thiamine reversed both neurologic and gastrointestinal symptoms within hours. It is hard to diagnose gastrointestinal beriberi since the symptoms are nonspecific. The patient underwent 11 emergency room visits, 3 hospital admissions, and laparoscopic cystectomy within 2 months, but the gastrointestinal symptoms continued to progress. Two months after the onset of gastrointestinal symptoms, external ophthalmoplegia appeared, and, therefore, intravenous thiamine was given. The simultaneous resolution of the debilitating gastrointestinal symptoms and external ophthalmoplegia was unique. Thiamine deficiency remains underdiagnosed and should be considered in patients who develop unexplained gastroparesis or autonomic nervous failure of the digestive system, even in the nonalcoholic population.
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spelling doaj.art-0b0ed0ce31cc44dba7770a419187d6262022-12-21T22:48:22ZengKarger PublishersCase Reports in Neurology1662-680X2019-04-0111112413110.1159/000499601499601Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy DrinkingElysia TjongYen-Yi PengAn otherwise healthy 30-year-old male acquired gastrointestinal beriberi and subsequent Wernicke’s encephalopathy after 1 session of heavy drinking. Nausea, vomiting, and anorexia relentlessly progressed. The patient developed external ophthalmoplegia after 2 months. Intravenous 1,000 mg thiamine reversed both neurologic and gastrointestinal symptoms within hours. It is hard to diagnose gastrointestinal beriberi since the symptoms are nonspecific. The patient underwent 11 emergency room visits, 3 hospital admissions, and laparoscopic cystectomy within 2 months, but the gastrointestinal symptoms continued to progress. Two months after the onset of gastrointestinal symptoms, external ophthalmoplegia appeared, and, therefore, intravenous thiamine was given. The simultaneous resolution of the debilitating gastrointestinal symptoms and external ophthalmoplegia was unique. Thiamine deficiency remains underdiagnosed and should be considered in patients who develop unexplained gastroparesis or autonomic nervous failure of the digestive system, even in the nonalcoholic population.https://www.karger.com/Article/FullText/499601Gastrointestinal beriberiWernicke’s encephalopathyThiamine
spellingShingle Elysia Tjong
Yen-Yi Peng
Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy Drinking
Case Reports in Neurology
Gastrointestinal beriberi
Wernicke’s encephalopathy
Thiamine
title Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy Drinking
title_full Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy Drinking
title_fullStr Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy Drinking
title_full_unstemmed Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy Drinking
title_short Gastrointestinal Beriberi and Wernicke’s Encephalopathy Triggered by One Session of Heavy Drinking
title_sort gastrointestinal beriberi and wernicke s encephalopathy triggered by one session of heavy drinking
topic Gastrointestinal beriberi
Wernicke’s encephalopathy
Thiamine
url https://www.karger.com/Article/FullText/499601
work_keys_str_mv AT elysiatjong gastrointestinalberiberiandwernickesencephalopathytriggeredbyonesessionofheavydrinking
AT yenyipeng gastrointestinalberiberiandwernickesencephalopathytriggeredbyonesessionofheavydrinking