Mechanism and effects of STING–IFN-I pathway on nociception: A narrative review

Since the discovery of STING in 2008, numerous studies have investigated its functions in immunity, inflammation, and cancer. STING activates downstream molecules including IFN-I, NLRP3, and NF-κB. The STING–IFN-I pathway plays a vital role in nociception. After receiving the upstream signal, STING...

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書目詳細資料
Main Authors: Jinghan Yang, Hui Ding, Bo Shuai, Yan Zhang
格式: Article
語言:English
出版: Frontiers Media S.A. 2023-01-01
叢編:Frontiers in Molecular Neuroscience
主題:
在線閱讀:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1081288/full