Mechanism and effects of STING–IFN-I pathway on nociception: A narrative review
Since the discovery of STING in 2008, numerous studies have investigated its functions in immunity, inflammation, and cancer. STING activates downstream molecules including IFN-I, NLRP3, and NF-κB. The STING–IFN-I pathway plays a vital role in nociception. After receiving the upstream signal, STING...
Main Authors: | , , , |
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格式: | Article |
語言: | English |
出版: |
Frontiers Media S.A.
2023-01-01
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叢編: | Frontiers in Molecular Neuroscience |
主題: | |
在線閱讀: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.1081288/full |