Submandibular gland carcinoma ex pleomorphic adenoma clinically mimicking a benign lesion
Carcinoma expleomorphic adenoma (CXPA) is a malignant carcinoma arising from a primary or recurrent benign pleomorphic adenoma. The lesion is recognized to be an aggressive malignancy with high recurrence rates and a high metastatic rate. CXPA is commonly seen in the sixth or seventh decade of life...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-09-01
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| Series: | Oral and Maxillofacial Surgery Cases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214541920300274 |
| Summary: | Carcinoma expleomorphic adenoma (CXPA) is a malignant carcinoma arising from a primary or recurrent benign pleomorphic adenoma. The lesion is recognized to be an aggressive malignancy with high recurrence rates and a high metastatic rate. CXPA is commonly seen in the sixth or seventh decade of life and shows a predilection for females. It accounts for approximately 3–5% of all salivary neoplasms and 12% of all salivary gland malignancies. Histologically, CXPA is characterized by the presence of both epithelial and mesenchymal components. We present an unusual case of a submandibular gland CXPA that clinically mimicked a benign tumour. The case offers an interesting perspective on the management challenges and associated prognostic significance after a follow-up evaluation of 6 years. |
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| ISSN: | 2214-5419 |