The motive forces in DNA-enabled nanomachinery
Summary: Building machines that can augment or replace human efforts to accomplish complex tasks is one of central topics for humanity. Especially, nanomachines made of discrete numbers of molecular components can perform intended mechanical movements in a predetermined manner. Utilizing free energi...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224006746 |
| _version_ | 1827311777615970304 |
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| author | Tao Zhang Huajie Liu |
| author_facet | Tao Zhang Huajie Liu |
| author_sort | Tao Zhang |
| collection | DOAJ |
| description | Summary: Building machines that can augment or replace human efforts to accomplish complex tasks is one of central topics for humanity. Especially, nanomachines made of discrete numbers of molecular components can perform intended mechanical movements in a predetermined manner. Utilizing free energies of Watson-Crick base pairing, different types of DNA nanomachines have been invented to operate intended stepwise or autonomous actions with external stimuli, and we here summarized the motive forces that drive DNA-based nanomachineries. DNA tweezers, DNA origami actuators, DNA walkers, and DNA machine-enabled bulk sensing are discussed including structural motif design, toehold creations for strands displacement reactions, and other input forces, as well as examples of biological motor-driven hybrid nanomachines. By addressing these prototypical artificial nanodevices, we envision future focuses should include developing various input energies, host cell-assisted structure self-replication, and nonequilibrium transportations. |
| first_indexed | 2024-04-24T20:24:26Z |
| format | Article |
| id | doaj.art-0b17a4d793a3478d8a971d73c23e3ed7 |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-04-24T20:24:26Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-0b17a4d793a3478d8a971d73c23e3ed72024-03-22T05:40:26ZengElsevieriScience2589-00422024-04-01274109453The motive forces in DNA-enabled nanomachineryTao Zhang0Huajie Liu1Department of Applied Chemistry, School of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, China; Corresponding authorSchool of Chemical Science and Engineering, Shanghai Research Institute for Intelligent Autonomous Systems, Key Laboratory of Advanced Civil Engineering Materials of Ministry of Education, Tongji University, Shanghai 200092, China; Corresponding authorSummary: Building machines that can augment or replace human efforts to accomplish complex tasks is one of central topics for humanity. Especially, nanomachines made of discrete numbers of molecular components can perform intended mechanical movements in a predetermined manner. Utilizing free energies of Watson-Crick base pairing, different types of DNA nanomachines have been invented to operate intended stepwise or autonomous actions with external stimuli, and we here summarized the motive forces that drive DNA-based nanomachineries. DNA tweezers, DNA origami actuators, DNA walkers, and DNA machine-enabled bulk sensing are discussed including structural motif design, toehold creations for strands displacement reactions, and other input forces, as well as examples of biological motor-driven hybrid nanomachines. By addressing these prototypical artificial nanodevices, we envision future focuses should include developing various input energies, host cell-assisted structure self-replication, and nonequilibrium transportations.http://www.sciencedirect.com/science/article/pii/S2589004224006746Supramolecular chemistryBiochemistry |
| spellingShingle | Tao Zhang Huajie Liu The motive forces in DNA-enabled nanomachinery iScience Supramolecular chemistry Biochemistry |
| title | The motive forces in DNA-enabled nanomachinery |
| title_full | The motive forces in DNA-enabled nanomachinery |
| title_fullStr | The motive forces in DNA-enabled nanomachinery |
| title_full_unstemmed | The motive forces in DNA-enabled nanomachinery |
| title_short | The motive forces in DNA-enabled nanomachinery |
| title_sort | motive forces in dna enabled nanomachinery |
| topic | Supramolecular chemistry Biochemistry |
| url | http://www.sciencedirect.com/science/article/pii/S2589004224006746 |
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