Passing the Baton: Substrate Channelling in Respiratory Metabolism
Despite species-specific differences in the pathways of respiratory metabolism are remarkably conserved across the kingdoms of life with glycolysis, the tricarboxylic acid cycle, and mitochondrial electron transport chain representing the major components of the process in the vast majority of organ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Association for the Advancement of Science (AAAS)
2018-01-01
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| Series: | Research |
| Online Access: | http://dx.doi.org/10.1155/2018/1539325 |
| _version_ | 1827333534293950464 |
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| author | Alisdair R. Fernie Youjun Zhang Lee J. Sweetlove |
| author_facet | Alisdair R. Fernie Youjun Zhang Lee J. Sweetlove |
| author_sort | Alisdair R. Fernie |
| collection | DOAJ |
| description | Despite species-specific differences in the pathways of respiratory metabolism are remarkably conserved across the kingdoms of life with glycolysis, the tricarboxylic acid cycle, and mitochondrial electron transport chain representing the major components of the process in the vast majority of organisms. In addition to being of critical importance in fueling life itself these pathways serve as interesting case studies for substrate channelling with research on this theme having been carried out for over 40 years. Here we provide a cross-kingdom review of the ample evidence for protein-protein interaction and enzyme assemblies within the three component pathways as well as describing the scarcer available evidence for substrate channelling itself. |
| first_indexed | 2024-03-07T17:27:49Z |
| format | Article |
| id | doaj.art-0b1a0f1ee7e14863805b08928e9d7d69 |
| institution | Directory Open Access Journal |
| issn | 2639-5274 |
| language | English |
| last_indexed | 2024-03-07T17:27:49Z |
| publishDate | 2018-01-01 |
| publisher | American Association for the Advancement of Science (AAAS) |
| record_format | Article |
| series | Research |
| spelling | doaj.art-0b1a0f1ee7e14863805b08928e9d7d692024-03-02T18:34:43ZengAmerican Association for the Advancement of Science (AAAS)Research2639-52742018-01-01201810.1155/2018/1539325Passing the Baton: Substrate Channelling in Respiratory MetabolismAlisdair R. Fernie0Youjun Zhang1Lee J. Sweetlove2Max-Planck-Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany; Center of Plant System Biology and Biotechnology, 4000 Plovdiv, BulgariaMax-Planck-Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476 Potsdam-Golm, Germany; Center of Plant System Biology and Biotechnology, 4000 Plovdiv, BulgariaDepartment of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UKDespite species-specific differences in the pathways of respiratory metabolism are remarkably conserved across the kingdoms of life with glycolysis, the tricarboxylic acid cycle, and mitochondrial electron transport chain representing the major components of the process in the vast majority of organisms. In addition to being of critical importance in fueling life itself these pathways serve as interesting case studies for substrate channelling with research on this theme having been carried out for over 40 years. Here we provide a cross-kingdom review of the ample evidence for protein-protein interaction and enzyme assemblies within the three component pathways as well as describing the scarcer available evidence for substrate channelling itself.http://dx.doi.org/10.1155/2018/1539325 |
| spellingShingle | Alisdair R. Fernie Youjun Zhang Lee J. Sweetlove Passing the Baton: Substrate Channelling in Respiratory Metabolism Research |
| title | Passing the Baton: Substrate Channelling in Respiratory Metabolism |
| title_full | Passing the Baton: Substrate Channelling in Respiratory Metabolism |
| title_fullStr | Passing the Baton: Substrate Channelling in Respiratory Metabolism |
| title_full_unstemmed | Passing the Baton: Substrate Channelling in Respiratory Metabolism |
| title_short | Passing the Baton: Substrate Channelling in Respiratory Metabolism |
| title_sort | passing the baton substrate channelling in respiratory metabolism |
| url | http://dx.doi.org/10.1155/2018/1539325 |
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