Rectal cancer survival in a Brazilian Cancer Reference Unit
Colorectal cancer is one of the most common malign tumors in men and women all over the world. In spite of prevention advances in the last few years, worldwide incidence remains significant, about one million per year. Objectives: Evaluate rectal cancer survival in patients diagnosed and surgically...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2016-10-01
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| Series: | Journal of Coloproctology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2237936316300533 |
| _version_ | 1818620233675440128 |
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| author | Romualdo da Silva Corrêa Francisco Edílson Leite Pinto Junior Lucas Vinícius Silva dos Santos Mariana Carlos de Góis Rumenick Pereira da Silva Hylarina Montenegro Diniz Silva |
| author_facet | Romualdo da Silva Corrêa Francisco Edílson Leite Pinto Junior Lucas Vinícius Silva dos Santos Mariana Carlos de Góis Rumenick Pereira da Silva Hylarina Montenegro Diniz Silva |
| author_sort | Romualdo da Silva Corrêa |
| collection | DOAJ |
| description | Colorectal cancer is one of the most common malign tumors in men and women all over the world. In spite of prevention advances in the last few years, worldwide incidence remains significant, about one million per year. Objectives: Evaluate rectal cancer survival in patients diagnosed and surgically treated at the Cancer Reference Unit at Rio Grande do Norte State, Brazil. Methods: Observational retrospective study composed by 135 patients assisted from 2007 to 2014 at Doctor Luiz Antonio Hospital, Natal, Brazil. Data were collected from the patient records revision and survival rates were calculated and analyzed by non-parametric Kaplan–Meier and Wilcoxon tests, respectively. All patients were submitted to surgical treatment, chemotherapy and/or radiotherapy. Results: Overall survival was 62% in seven years, while disease-free survival in one, three and five years was 91.7%, 75.5% and 72.1%, respectively. Conclusion: Overall survival and disease-free survival remained enhanced until the end of the study, suggesting that the treatment protocols used in the institution have shown to be effective. Resumo: O câncer colorretal é um dos tumores malignos mais comuns em homens e mulheres em todo o mundo. Apesar das melhorias na prevenção nos últimos anos, a incidência global ainda é expressiva, cerca de um milhão por ano. Objetivos: Avaliar a sobrevida do câncer de reto nos pacientes diagnosticados e tratados cirurgicamente na Unidade de Referência do Câncer no Rio Grande do Norte, Brasil. Métodos: Estudo observacional retrospectivo composto por 135 pacientes, compreendido no período de 2007 a 2014 no Hospital Dr. Luiz Antônio, Natal, Brasil. Os dados foram coletados através da revisão de prontuários e as sobrevidas foram calculadas e comparadas utilizando, respectivamente, os métodos não-paramétricos de Kaplan-Meier e teste de Wilcoxon. Todos os pacientes foram submetidos a tratamento cirúrgico, quimioterápico e radioterápico. Resultados: A sobrevida global foi de 62% em sete anos, sendo a sobrevida livre de doença em um, três e cinco anos de 91,7%, 75,5% e 72,1%, respectivamente. Conclusão: As sobrevidas global e livre da doença são elevadas até o encerramento do estudo, o que demonstra que os protocolos de tratamento utilizados na instituição têm se mostrado eficazes. Keywords: Colorectal cancer, Surgery, Survival, Palavras-chave: Câncer colorretal, Cirurgia, Sobrevida |
| first_indexed | 2024-12-16T17:50:08Z |
| format | Article |
| id | doaj.art-0b1a85c8de684fb4954b5e48bccc92b7 |
| institution | Directory Open Access Journal |
| issn | 2237-9363 |
| language | English |
| last_indexed | 2024-12-16T17:50:08Z |
| publishDate | 2016-10-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Journal of Coloproctology |
| spelling | doaj.art-0b1a85c8de684fb4954b5e48bccc92b72022-12-21T22:22:20ZengThieme Revinter Publicações Ltda.Journal of Coloproctology2237-93632016-10-01364203207Rectal cancer survival in a Brazilian Cancer Reference UnitRomualdo da Silva Corrêa0Francisco Edílson Leite Pinto Junior1Lucas Vinícius Silva dos Santos2Mariana Carlos de Góis3Rumenick Pereira da Silva4Hylarina Montenegro Diniz Silva5Liga Norte Riograndense Contra o Câncer, Natal, RN, Brazil; Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil; Universidade Potiguar (UnP), Natal, RN, Brazil; Corresponding author.Liga Norte Riograndense Contra o Câncer, Natal, RN, Brazil; Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil; Universidade Potiguar (UnP), Natal, RN, BrazilUniversidade Potiguar (UnP), Natal, RN, BrazilUniversidade Potiguar (UnP), Natal, RN, BrazilUniversidade Federal de Minas Gerais (UFMG), Departamento de Estatística, Belo Horizonte, MG, BrazilUniversidade Federal do Rio Grande do Norte (UFRN), Maternidade Escola Januário Cicco, Natal, RN, BrazilColorectal cancer is one of the most common malign tumors in men and women all over the world. In spite of prevention advances in the last few years, worldwide incidence remains significant, about one million per year. Objectives: Evaluate rectal cancer survival in patients diagnosed and surgically treated at the Cancer Reference Unit at Rio Grande do Norte State, Brazil. Methods: Observational retrospective study composed by 135 patients assisted from 2007 to 2014 at Doctor Luiz Antonio Hospital, Natal, Brazil. Data were collected from the patient records revision and survival rates were calculated and analyzed by non-parametric Kaplan–Meier and Wilcoxon tests, respectively. All patients were submitted to surgical treatment, chemotherapy and/or radiotherapy. Results: Overall survival was 62% in seven years, while disease-free survival in one, three and five years was 91.7%, 75.5% and 72.1%, respectively. Conclusion: Overall survival and disease-free survival remained enhanced until the end of the study, suggesting that the treatment protocols used in the institution have shown to be effective. Resumo: O câncer colorretal é um dos tumores malignos mais comuns em homens e mulheres em todo o mundo. Apesar das melhorias na prevenção nos últimos anos, a incidência global ainda é expressiva, cerca de um milhão por ano. Objetivos: Avaliar a sobrevida do câncer de reto nos pacientes diagnosticados e tratados cirurgicamente na Unidade de Referência do Câncer no Rio Grande do Norte, Brasil. Métodos: Estudo observacional retrospectivo composto por 135 pacientes, compreendido no período de 2007 a 2014 no Hospital Dr. Luiz Antônio, Natal, Brasil. Os dados foram coletados através da revisão de prontuários e as sobrevidas foram calculadas e comparadas utilizando, respectivamente, os métodos não-paramétricos de Kaplan-Meier e teste de Wilcoxon. Todos os pacientes foram submetidos a tratamento cirúrgico, quimioterápico e radioterápico. Resultados: A sobrevida global foi de 62% em sete anos, sendo a sobrevida livre de doença em um, três e cinco anos de 91,7%, 75,5% e 72,1%, respectivamente. Conclusão: As sobrevidas global e livre da doença são elevadas até o encerramento do estudo, o que demonstra que os protocolos de tratamento utilizados na instituição têm se mostrado eficazes. Keywords: Colorectal cancer, Surgery, Survival, Palavras-chave: Câncer colorretal, Cirurgia, Sobrevidahttp://www.sciencedirect.com/science/article/pii/S2237936316300533 |
| spellingShingle | Romualdo da Silva Corrêa Francisco Edílson Leite Pinto Junior Lucas Vinícius Silva dos Santos Mariana Carlos de Góis Rumenick Pereira da Silva Hylarina Montenegro Diniz Silva Rectal cancer survival in a Brazilian Cancer Reference Unit Journal of Coloproctology |
| title | Rectal cancer survival in a Brazilian Cancer Reference Unit |
| title_full | Rectal cancer survival in a Brazilian Cancer Reference Unit |
| title_fullStr | Rectal cancer survival in a Brazilian Cancer Reference Unit |
| title_full_unstemmed | Rectal cancer survival in a Brazilian Cancer Reference Unit |
| title_short | Rectal cancer survival in a Brazilian Cancer Reference Unit |
| title_sort | rectal cancer survival in a brazilian cancer reference unit |
| url | http://www.sciencedirect.com/science/article/pii/S2237936316300533 |
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